Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053627 | 0.97 | MAPT (0.43) | MAPTHTTHDAC11EGFRHDAC1 | |
| SCHEMBL28053637 | 0.76 | PSMB8 (0.46) | HDAC11HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL28053634 | 0.76 | PSMB8 (0.50) | HDAC1HDAC3HDAC2HDAC10HDAC8 | |
| SCHEMBL28053558 | 0.76 | HDAC11 (0.56) | HTTHDAC11HDAC1HDAC3HDAC4 | |
| SCHEMBL28261763 | 0.76 | APP (0.41) | HTTHDAC11ESR1APP | |
| SCHEMBL28261739 | 0.75 | APP (0.42) | HTTHDAC11ESR1APP | |
| SCHEMBL28260474 | 0.75 | APP (0.42) | HTTHDAC11ESR1APP | |
| SCHEMBL28260483 | 0.75 | APP (0.42) | HTTHDAC11ESR1APP | |
| SCHEMBL28624872 | 0.74 | HDAC11 (0.41) | MAPTHDAC11HDAC1HDAC3HDAC4 | |
| SCHEMBL28624764 | 0.74 | HDAC11 (0.41) | MAPTHDAC11HDAC1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272928-A | Alkenyl amide triazole compound and synthetic method thereof | UNIV SHAANXI NORMAL | 2016-01-27 | — | — | CN | disclosed |