Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28826249 | 0.97 | MAPT (0.44) | MAPTHTTHDAC11PKMHPGD | |
| SCHEMBL28053637 | 0.80 | PSMB8 (0.46) | HDAC11PSMB8PSMB5PSMB9HDAC3 | |
| SCHEMBL28261763 | 0.79 | APP (0.41) | HTTHDAC11PSMB8PSMB5PSMB9 | |
| SCHEMBL28053634 | 0.79 | PSMB8 (0.50) | PKMHPGDL3MBTL1PSMB8PSMB5 | |
| SCHEMBL28053558 | 0.79 | HDAC11 (0.56) | HTTHDAC11HPGDL3MBTL1PSMB8 | |
| SCHEMBL28260474 | 0.78 | APP (0.42) | HTTHDAC11PSMB8PSMB5PSMB9 | |
| SCHEMBL28260483 | 0.78 | APP (0.42) | HTTHDAC11PSMB8PSMB5PSMB9 | |
| SCHEMBL28261739 | 0.78 | APP (0.42) | HTTHDAC11PSMB8PSMB5PSMB9 | |
| SCHEMBL28640947 | 0.77 | PSMB8 (0.41) | MAPTHDAC11HPGDPSMB8PSMB5 | |
| SCHEMBL28630349 | 0.77 | PSMB8 (0.41) | MAPTHDAC11HPGDPSMB8PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272928-A | Alkenyl amide triazole compound and synthetic method thereof | UNIV SHAANXI NORMAL | 2016-01-27 | — | — | CN | disclosed |