Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL432082 | 1.00 | DNM1 (0.68) | DNM1EPHX2KDM4ECNR1ALDH1A1 | |
| Lactic Acid SCHEMBL3336829 | 0.92 | DNM1 (0.80) | DNM1EPHX2KDM4EMEN1KMT2A | |
| Lactic Acid SCHEMBL3863099 | 0.92 | DNM1 (0.80) | DNM1EPHX2KDM4EMEN1KMT2A | |
| Lactic Acid SCHEMBL128277 | 0.92 | DNM1 (0.80) | DNM1EPHX2KDM4EMEN1KMT2A | |
| Lactic Acid SCHEMBL428727 | 0.92 | DNM1 (0.80) | DNM1EPHX2KDM4EMEN1KMT2A | |
| SCHEMBL25134837 | 0.91 | DNM1 (0.82) | DNM1EPHX2KDM4ECNR1ALDH1A1 | |
| SCHEMBL9505196 | 0.91 | DNM1 (0.82) | DNM1EPHX2KDM4ECNR1ALDH1A1 | |
| SCHEMBL75309 | 0.91 | DNM1 (0.82) | DNM1EPHX2KDM4ECNR1ALDH1A1 | |
| SCHEMBL6417641 | 0.91 | DNM1 (0.82) | DNM1EPHX2KDM4ECNR1ALDH1A1 | |
| SCHEMBL14060400 | 0.91 | DNM1 (0.82) | DNM1EPHX2KDM4ECNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109382082-A | Carrier and preparation method thereof and fischer-tropsch synthetic catalyst and Fischer-Tropsch synthesis method | 中国石油化工股份有限公司 | 2019-02-26 | — | — | CN | disclosed |
| CN-109382081-A | Carrier and preparation method thereof and fischer-tropsch synthetic catalyst and Fischer-Tropsch synthesis method | 中国石油化工股份有限公司 | 2019-02-26 | — | — | CN | disclosed |
| CN-109382096-A | Ruthenium-based catalyst and preparation method thereof and Fischer-Tropsch synthesis method | 中国石油化工股份有限公司 | 2019-02-26 | — | — | CN | disclosed |
| CN-102276732-B | Cellulose interpolymers and method for oxidation | EASTMAN CHEM CO. (US) | 2016-01-20 | — | — | CN | disclosed |