Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL28053597 | 1.00 | DNM1 (0.68) | DNM1EPHX2KDM4ECNR1ALDH1A1 | |
| Lactic Acid SCHEMBL3336829 | 0.92 | DNM1 (0.80) | DNM1EPHX2KDM4EMEN1KMT2A | |
| Lactic Acid SCHEMBL3863099 | 0.92 | DNM1 (0.80) | DNM1EPHX2KDM4EMEN1KMT2A | |
| Lactic Acid SCHEMBL128277 | 0.92 | DNM1 (0.80) | DNM1EPHX2KDM4EMEN1KMT2A | |
| Lactic Acid SCHEMBL428727 | 0.92 | DNM1 (0.80) | DNM1EPHX2KDM4EMEN1KMT2A | |
| SCHEMBL25134837 | 0.91 | DNM1 (0.82) | DNM1EPHX2KDM4ECNR1ALDH1A1 | |
| SCHEMBL9505196 | 0.91 | DNM1 (0.82) | DNM1EPHX2KDM4ECNR1ALDH1A1 | |
| SCHEMBL75309 | 0.91 | DNM1 (0.82) | DNM1EPHX2KDM4ECNR1ALDH1A1 | |
| SCHEMBL6417641 | 0.91 | DNM1 (0.82) | DNM1EPHX2KDM4ECNR1ALDH1A1 | |
| SCHEMBL14060400 | 0.91 | DNM1 (0.82) | DNM1EPHX2KDM4ECNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113892-A1 | Antimicrobial wash formulations including amidoamine-based cationic surfactants | SILVER POINT FINANCE, LLC, AS COLLATERAL AGENT | 2008-05-15 | — | — | US | claimed |
| US-20020155962-A1 | Nonaqueous hair styling composition and method of use | ANDREW JERGENS COMPANY, THE | 2002-10-24 | — | — | US | claimed |
| US-11447640-B2 | Encapsulated materials with improved properties | SUN CHEMICAL CORPORATION (US) | 2022-09-20 | — | — | US | disclosed |
| EP-3500601-B1 | ENCAPSULATED MATERIALS WITH IMPROVED PROPERTIES | SUN CHEMICAL CORP (US) | 2021-07-28 | — | — | EP | disclosed |
| US-20210214561-A1 | ENCAPSULATED MATERIALS WITH IMPROVED PROPERTIES | SUN CHEMICAL CORPORATION (US) | 2021-07-15 | — | — | US | disclosed |
| US-10722439-B2 | Hair care products | HENKEL AG & CO. KGAA (DE) | 2020-07-28 | — | — | US | disclosed |
| US-20200170912-A1 | COMPOSITION FOR THE CARE OF HUMAN HAIR | HENKEL AG & CO. KGAA (DE) | 2020-06-04 | — | — | US | disclosed |
| EP-3500601-A1 | ENCAPSULATED MATERIALS WITH IMPROVED PROPERTIES | Sun Chemical Corporation (US) | 2019-06-26 | — | — | EP | disclosed |
| WO-2019109243-A1 | Cosmetic composition for permanently changing the shape of keratinous fibers | HENKEL AG & CO.KGAA (DE) | 2019-06-13 | — | — | WO | disclosed |
| US-20190021968-A1 | HAIR CARE PRODUCTS | HENKEL AG & CO. KGAA (DE) | 2019-01-24 | — | — | US | disclosed |
| WO-2018035325-A1 | ENCAPSULATED MATERIALS WITH IMPROVED PROPERTIES | SUN CHEMICAL CORPORATION (US) | 2018-02-22 | — | — | WO | disclosed |
| EP-0523388-B1 | Aerosol hair spray | CURTIS HELENE IND INC (US) | 1995-11-15 | — | — | EP | disclosed |
| US-5362486-A | In-situ polymerization of oligomers onto hair | HELENE CURTIS, INC. (US) | 1994-11-08 | — | — | US | disclosed |
| US-5286477-A | Ethyl methacrylate-vinylpyrrolidone-methacrylic acid terpolymer fixative, dimethyl ether propellant | HELENE CURTIS, INC. (US) | 1994-02-15 | — | — | US | disclosed |
| EP-0524427-A2 | Aqueous hair styling aid | HELENE CURTIS, INC. (US) | 1993-01-27 | — | — | EP | disclosed |
| EP-0524346-A1 | Composition and method for protecting hair against thermal degradation and to aid in hair styling | HELENE CURTIS, INC. (US) | 1993-01-27 | — | — | EP | disclosed |
| EP-0523388-A2 | Aerosol hair spray | HELENE CURTIS, INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5164177-A | Aqueous aerosol or nonaerosol hair spray | HELENE CURTIS, INC. (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0467235-A1 | Hair conditioning shampoo | HELENE CURTIS, INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| US-5078990-A | Contain long chain alkyl sulfate and/or ether sulfates, | HELENE CURTIS, INC. (US) | 1992-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10722439-B2 | Hair care products | ACMSD, ARG1, NACA | DNM1 1430/4885EPHX2 1968/4885KDM4E 1464/4885 |
| US-20190021968-A1 | HAIR CARE PRODUCTS | ACMSD, ARG1, NACA | DNM1 1567/4885EPHX2 2143/4885KDM4E 1334/4885 |
| US-20200170912-A1 | COMPOSITION FOR THE CARE OF HUMAN HAIR | POLR1C, KRT18, SLC27A1 | DNM1 618/4885EPHX2 3829/4885KDM4E 1720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.