Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.80 |
| ▸ | FAAH | O00519 | 8/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL3336829 | 1.00 | DNM1 (0.80) | DNM1FAAHNAAACASP2EPHX2 | |
| Lactic Acid SCHEMBL128277 | 1.00 | DNM1 (0.80) | DNM1FAAHNAAACASP2EPHX2 | |
| Lactic Acid SCHEMBL428727 | 1.00 | DNM1 (0.80) | DNM1FAAHNAAACASP2EPHX2 | |
| Lactic Acid SCHEMBL25266814 | 0.93 | DNM1 (0.79) | DNM1FAAHNAAACASP2EPHX2 | |
| Lactic Acid SCHEMBL432082 | 0.92 | DNM1 (0.68) | DNM1FAAHEPHX2KDM4EMEN1 | |
| Lactic Acid SCHEMBL28053597 | 0.92 | DNM1 (0.68) | DNM1FAAHEPHX2KDM4EMEN1 | |
| SCHEMBL8660980 | 0.89 | DNM1 (1.00) | DNM1FAAHNAAACASP2EPHX2 | |
| SCHEMBL5383341 | 0.89 | DNM1 (1.00) | DNM1FAAHNAAACASP2EPHX2 | |
| SCHEMBL9565176 | 0.89 | DNM1 (1.00) | DNM1FAAHNAAACASP2EPHX2 | |
| SCHEMBL19281112 | 0.89 | DNM1 (1.00) | DNM1FAAHNAAACASP2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517842-B2 | Antimicrobial wash formulations including amidoamine-based cationic surfactants | GOJO INDUSTRIES, INC. (US) | 2009-04-14 | — | — | US | claimed |
| US-20080113892-A1 | Antimicrobial wash formulations including amidoamine-based cationic surfactants | SILVER POINT FINANCE, LLC, AS COLLATERAL AGENT | 2008-05-15 | — | — | US | claimed |
| US-7517842-B2 | Antimicrobial wash formulations including amidoamine-based cationic surfactants | GOJO INDUSTRIES, INC. (US) | 2009-04-14 | — | — | US | disclosed |
| US-20080113892-A1 | Antimicrobial wash formulations including amidoamine-based cationic surfactants | SILVER POINT FINANCE, LLC, AS COLLATERAL AGENT | 2008-05-15 | — | — | US | disclosed |