Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 8/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 8/20 | 0.50 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.41 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.41 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.41 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.41 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053627 | 0.79 | MAPT (0.43) | PSMB8PSMB5PSMB9HPGDPKM | |
| SCHEMBL28826249 | 0.76 | MAPT (0.44) | HPGDPKML3MBTL1HDAC3HDAC1 | |
| SCHEMBL24785692 | 0.68 | PSMB8 (0.51) | PSMB8PSMB5PSMB9SMYD3HDAC3 | |
| SCHEMBL18850877 | 0.67 | PSMB8 (0.54) | PSMB8PSMB5PSMB9SMYD3HDAC3 | |
| SCHEMBL18850919 | 0.67 | PSMB8 (0.54) | PSMB8PSMB5PSMB9SMYD3HDAC3 | |
| SCHEMBL28053628 | 0.65 | PKM (0.44) | HPGDPKML3MBTL1NAAAGAA | |
| SCHEMBL19701612 | 0.65 | SMYD3 (0.54) | PSMB8PSMB5PSMB9SMYD3LGALS3 | |
| SCHEMBL28261739 | 0.65 | APP (0.42) | PSMB8PSMB5PSMB9NAAA | |
| SCHEMBL28260474 | 0.65 | APP (0.42) | PSMB8PSMB5PSMB9NAAA | |
| SCHEMBL28053555 | 0.65 | PKM (0.43) | HPGDPKML3MBTL1NAAAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272928-A | Alkenyl amide triazole compound and synthetic method thereof | UNIV SHAANXI NORMAL | 2016-01-27 | — | — | CN | disclosed |