SCHEMBL28053714

SCHEMBL28053714

C=CCOC(=O)C(CC(CCC)c1ccccc1)(C(=O)O)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
ALDH1A1 P00352 5/20 0.35
CASP1 P29466 3/20 0.35
TSHR P16473 2/20 0.35
CHRM2 P08172 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
MAPT P10636 1/20 0.33
CTSL P07711 1/20 0.33
CTSB P07858 1/20 0.33
CTSH P09668 1/20 0.33
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
NPSR1 Q6W5P4 2/20 0.33
PKM P14618 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28053809 0.91 CYP3A4 (0.38) CYP3A4ALDH1A1CASP1TSHRCHRM2
SCHEMBL27933151 0.83 CYP3A4 (0.39) CYP3A4ALDH1A1CASP1TSHRCHRM2
SCHEMBL28053819 0.83 AOC3 (0.41) MAPTNPSR1PKMSMN1; SMN2LMNA
SCHEMBL28053816 0.78 RIPK1 (0.38) CYP3A4ALDH1A1CASP1TSHRCHRM2
SCHEMBL28053761 0.77 CYP3A4 (0.38) CYP3A4ALDH1A1CASP1TSHRCHRM2
SCHEMBL28003868 0.74 CYP3A4 (0.53) CYP3A4ALDH1A1CASP1TSHRMAPT
SCHEMBL27948399 0.72 CYP3A4 (0.42) CYP3A4ALDH1A1CASP1TSHRNPSR1
SCHEMBL28053820 0.72 LMNA (0.40) CYP3A4ALDH1A1MAPTNPSR1PKM
SCHEMBL28663788 0.71 TDP1 (0.46) CYP3A4ALDH1A1TSHRCHRM2CHRM1
SCHEMBL28235232 0.71 CYP2C19 (0.49) CYP3A4ALDH1A1TSHRCHRM1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103459467-B Polybenzoxazole resin and precursor thereof MITSUBISHI GAS CHEMICAL CO.,INC. (JP) 2016-04-06 CN claimed
CN-103459467-B Polybenzoxazole resin and precursor thereof MITSUBISHI GAS CHEMICAL CO.,INC. (JP) 2016-04-06 CN disclosed