SCHEMBL28053761

SCHEMBL28053761

C=CCOC(=O)C(C(=O)O)(c1ccccc1)C(CCC)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.38
ALDH1A1 P00352 5/20 0.37
TSHR P16473 2/20 0.37
NPSR1 Q6W5P4 2/20 0.34
CASP1 P29466 4/20 0.34
CYP2C19 P33261 1/20 0.34
HSD17B10 Q99714 1/20 0.34
SCN1A P35498 2/20 0.34
SCN2A Q99250 2/20 0.34
SCN3A Q9NY46 2/20 0.34
PKM P14618 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
KMT2A Q03164 1/20 0.34
CTSL P07711 1/20 0.34
CTSB P07858 1/20 0.34
CTSH P09668 1/20 0.34
CTSS P25774 1/20 0.34
CTSK P43235 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28053822 0.93 CTSK (0.39) CYP3A4ALDH1A1TSHRNPSR1CASP1
SCHEMBL27948490 0.90 CYP3A4 (0.39) CYP3A4ALDH1A1TSHRNPSR1CASP1
SCHEMBL27932641 0.83 CYP3A4 (0.41) CYP3A4ALDH1A1TSHRNPSR1CASP1
SCHEMBL28053821 0.82 CNR1 (0.41) NPSR1CYP2C19MEN1KMT2A
SCHEMBL28053714 0.77 CYP3A4 (0.36) CYP3A4ALDH1A1TSHRNPSR1CASP1
SCHEMBL28053719 0.74 POLB (0.46) ALDH1A1NPSR1MEN1KMT2ACTSL
SCHEMBL28235232 0.72 CYP2C19 (0.49) CYP3A4ALDH1A1TSHRCYP2C19HSD17B10
SCHEMBL11783872 0.71 TSHR (0.47) CYP3A4ALDH1A1TSHRNPSR1CYP2C19
SCHEMBL9879540 0.71 CYP3A4 (0.45) CYP3A4ALDH1A1TSHRNPSR1CYP2C19
SCHEMBL6472435 0.71 ALDH1A1 (0.50) CYP3A4ALDH1A1TSHRNPSR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103459467-B Polybenzoxazole resin and precursor thereof MITSUBISHI GAS CHEMICAL CO.,INC. (JP) 2016-04-06 CN claimed
CN-103459467-B Polybenzoxazole resin and precursor thereof MITSUBISHI GAS CHEMICAL CO.,INC. (JP) 2016-04-06 CN disclosed