Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 8/20 | 0.60 |
| ▸ | MMP2 | P08253 | 8/20 | 0.60 |
| ▸ | MMP9 | P14780 | 8/20 | 0.60 |
| ▸ | EGFR | P00533 | 4/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053718 | 1.00 | MMP1 (0.60) | MMP1MMP2MMP9EGFRMAOB | |
| SCHEMBL28053554 | 0.80 | HDAC1 (0.53) | MMP1MMP2MMP9EGFRMAOB | |
| SCHEMBL10781392 | 0.79 | MEN1 (0.52) | MAOBHDAC3HDAC4HDAC1HDAC7 | |
| N-Phenylcinnamamide SCHEMBL3667414 | 0.77 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAOB | |
| N-Phenylcinnamamide SCHEMBL4205896 | 0.77 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAOB | |
| N-Phenylcinnamamide SCHEMBL2682029 | 0.77 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAOB | |
| SCHEMBL11590995 | 0.74 | EGFR (0.92) | MMP1MMP2MMP9EGFRMAOB | |
| SCHEMBL15482214 | 0.73 | MMP1 (0.83) | MMP1MMP2MMP9EGFRMAOB | |
| SCHEMBL28053632 | 0.72 | MEN1 (0.58) | MMP1MMP2MMP9EGFRHDAC1 | |
| SCHEMBL262818 | 0.71 | MMP1 (0.86) | MMP1MMP2MMP9EGFRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272928-A | Alkenyl amide triazole compound and synthetic method thereof | UNIV SHAANXI NORMAL | 2016-01-27 | — | — | CN | disclosed |