Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MMP1 | P03956 | 3/20 | 0.58 |
| ▸ | MMP2 | P08253 | 3/20 | 0.58 |
| ▸ | MMP9 | P14780 | 3/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 2/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053554 | 0.91 | HDAC1 (0.53) | MEN1KMT2APOLBMMP1MMP2 | |
| SCHEMBL28053553 | 0.74 | MAPT (0.47) | MEN1KMT2AMMP1MMP2MMP9 | |
| SCHEMBL28643460 | 0.74 | RAB9A (0.52) | MEN1KMT2APOLBALDH1A1KDM4E | |
| N-(4-Chlorophenyl)Cinnamamide SCHEMBL8684664 | 0.74 | MMP1 (1.00) | MEN1KMT2AMMP1MMP2MMP9 | |
| N-(4-Chlorophenyl)Cinnamamide SCHEMBL8684658 | 0.74 | MMP1 (1.00) | MEN1KMT2AMMP1MMP2MMP9 | |
| SCHEMBL28265446 | 0.74 | P2RX7 (0.54) | MEN1KMT2APOLBHDAC1HDAC2 | |
| SCHEMBL28637947 | 0.74 | P2RX7 (0.54) | MEN1KMT2APOLBHDAC1HDAC2 | |
| SCHEMBL28053718 | 0.72 | MMP1 (0.60) | MMP1MMP2MMP9EGFRHDAC1 | |
| SCHEMBL28053715 | 0.72 | MMP1 (0.60) | MMP1MMP2MMP9EGFRHDAC1 | |
| SCHEMBL15263182 | 0.71 | MMP1 (0.88) | MEN1KMT2AMMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272928-A | Alkenyl amide triazole compound and synthetic method thereof | UNIV SHAANXI NORMAL | 2016-01-27 | — | — | CN | disclosed |