Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.53 |
| ▸ | MMP1 | P03956 | 4/20 | 0.53 |
| ▸ | MMP2 | P08253 | 4/20 | 0.53 |
| ▸ | MMP9 | P14780 | 4/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053632 | 0.91 | MEN1 (0.58) | HDAC1HDAC2MMP1MMP2MMP9 | |
| SCHEMBL28053718 | 0.80 | MMP1 (0.60) | HDAC1HDAC2MMP1MMP2MMP9 | |
| SCHEMBL28053715 | 0.80 | MMP1 (0.60) | HDAC1HDAC2MMP1MMP2MMP9 | |
| SCHEMBL28265446 | 0.79 | P2RX7 (0.54) | HDAC1HDAC2P2RX7MEN1KMT2A | |
| SCHEMBL28637947 | 0.79 | P2RX7 (0.54) | HDAC1HDAC2P2RX7MEN1KMT2A | |
| SCHEMBL9840923 | 0.71 | MMP1 (0.73) | MMP1MMP2MMP9MAOBEGFR | |
| SCHEMBL6302448 | 0.71 | MMP1 (0.73) | MMP1MMP2MMP9MAOBEGFR | |
| SCHEMBL6302452 | 0.71 | MMP1 (0.73) | MMP1MMP2MMP9MAOBEGFR | |
| SCHEMBL2819653 | 0.70 | P2RX7 (1.00) | MAOAP2RX7KMT2ARAB9AMIF | |
| N-Phenylcinnamamide SCHEMBL3667414 | 0.70 | MMP1 (1.00) | MMP1MMP2MMP9MAOBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272928-A | Alkenyl amide triazole compound and synthetic method thereof | UNIV SHAANXI NORMAL | 2016-01-27 | — | — | CN | disclosed |