Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30073983 | 0.98 | CPT2 (0.40) | CPT2ACLYALDH1A1L3MBTL1 | |
| SCHEMBL30073984 | 0.98 | CPT2 (0.40) | CPT2ACLYALDH1A1L3MBTL1 | |
| SCHEMBL27361082 | 0.71 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL29244118 | 0.68 | ALDH1A1 (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL27811225 | 0.66 | PDE4A (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL736499 | 0.64 | CPT2 (0.48) | CPT2ACLYALDH1A1 | |
| SCHEMBL10620607 | 0.64 | CPT2 (0.48) | CPT2ACLYALDH1A1 | |
| SCHEMBL721349 | 0.64 | CPT2 (0.48) | CPT2ACLYALDH1A1 | |
| SCHEMBL22731538 | 0.63 | — | — | |
| SCHEMBL11817924 | 0.62 | CPT2 (0.46) | CPT2ACLYALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105492434-A | Heterobicycloaryl RORC2 inhibitors and methods of use thereof | PFIZER | 2016-04-13 | — | — | CN | disclosed |