SCHEMBL28053807

SCHEMBL28053807

CC(CCC(C(=O)O)(C(=O)O)c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 2/20 0.56
TRPA1 O75762 3/20 0.45
CNR1 P21554 2/20 0.44
CNR2 P34972 2/20 0.44
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
TAAR1 Q96RJ0 2/20 0.40
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
KIF11 P52732 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28826292 0.92 RIPK1 (0.50) RIPK1TRPA1CNR1CNR2CYP1A2
SCHEMBL28004294 0.84 CYP2D6 (0.46) CYP1A2CYP2D6KIF11
SCHEMBL15463388 0.83 CYP2D6 (0.44) RIPK1TRPA1CNR1CNR2CYP1A2
SCHEMBL28053712 0.81 KIF11 (0.41) RIPK1CNR1CNR2CYP1A2CYP2D6
SCHEMBL27665702 0.77 RIPK1 (0.61) RIPK1TRPA1CNR1CNR2CYP1A2
SCHEMBL27263782 0.74 CYP2C19 (0.44) CYP1A2CYP2D6KIF11
SCHEMBL21269261 0.73 CYP2C19 (0.42) CYP1A2CYP2D6KIF11
SCHEMBL21269765 0.73 CYP2C19 (0.42) CYP1A2CYP2D6KIF11
SCHEMBL21269871 0.73 CYP2C19 (0.42) CYP1A2CYP2D6KIF11
SCHEMBL28564931 0.73 CYP2D6 (0.48) CYP1A2CYP2D6KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103459467-B Polybenzoxazole resin and precursor thereof MITSUBISHI GAS CHEMICAL CO.,INC. (JP) 2016-04-06 CN claimed
CN-103459467-B Polybenzoxazole resin and precursor thereof MITSUBISHI GAS CHEMICAL CO.,INC. (JP) 2016-04-06 CN disclosed