SCHEMBL28054029

SCHEMBL28054029

Oc1ccc(CCCCl)cc1Cl

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 6/20 0.59
ALOX15 P16050 6/20 0.59
CA2 P00918 3/20 0.52
HSD17B10 Q99714 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
TSHR P16473 1/20 0.45
CA1 P00915 2/20 0.43
CYP19A1 P11511 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9745836 0.90 IGF1R (0.66) IGF1RALOX15CA2HSD17B10CYP1A2
SCHEMBL18986912 0.88 CA2 (0.55) IGF1RALOX15CA2HSD17B10CYP1A2
SCHEMBL10961370 0.88 IGF1R (0.69) IGF1RALOX15CA2HSD17B10CYP1A2
SCHEMBL9773533 0.85 CA2 (0.61) IGF1RALOX15CA2HSD17B10CYP1A2
SCHEMBL28040552 0.83 ALOX15 (0.75) IGF1RALOX15CA2HSD17B10CYP2D6
Formaldehyde SCHEMBL11417016 0.82 CA2 (0.55) IGF1RALOX15CA2HSD17B10CYP1A2
SCHEMBL574235 0.82 IGF1R (0.58) IGF1RALOX15CA2CA1
SCHEMBL10941414 0.82 IGF1R (0.58) IGF1RALOX15CA2HSD17B10CYP1A2
SCHEMBL11443994 0.81 IGF1R (0.60) IGF1RALOX15CYP1A2CYP2D6CYP2C19
SCHEMBL573937 0.81 IGF1R (0.61) IGF1RALOX15CA2HSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104744915-B There is the outward appearance of improvement and the poly carbonate resin composition of mobility 三星SDI株式会社 2017-01-04 CN disclosed
CN-104508042-B Thermoplastic resin composition and sheet using the same 三菱瓦斯化学株式会社 2016-10-19 CN disclosed
CN-105980156-A Multilayer body 帝人株式会社 2016-09-28 CN disclosed
CN-103958606-B Poly carbonate resin composition 第毛织株式会社 2016-09-28 CN disclosed
CN-103987771-B Flame-resistant polyalkylene terephthalate/polycarbonate compositions 科思创德国股份有限公司 2016-08-24 CN disclosed
CN-105867079-A Electrophotographic Photoreceptor, Process Cartridge and Image Forming Apparatus 富士施乐株式会社 2016-08-17 CN disclosed
CN-105793989-A Fabrication of IGZO oxide tft on high CTE, low retardation polymer films for LCD-TFT applications 科思创德国股份有限公司 2016-07-20 CN disclosed
CN-105765002-A Formable hard coated PC/PMMA coextruded films 科思创德国股份有限公司 2016-07-13 CN disclosed
CN-105739007-A Light Guide Plate and Method for Manufacturing the Same 三星SDI株式会社 2016-07-06 CN disclosed
CN-105722656-A METHOD FOR PRODUCING A MOULDED PART BY STRUCTURAL FOAM MOULDING, MOULDED PART OF AN EXPANDED THERMOPLASTIC MATERIAL AND USES THEREFOR 科思创德国股份有限公司 2016-06-29 CN disclosed
CN-105722668-A Multilayer structural component, method for the production thereof and use thereof 科思创德国股份有限公司 2016-06-29 CN disclosed
CN-105723543-A Battery module having a safety section, battery pack, and electric vehicle 科思创德国股份有限公司 2016-06-29 CN disclosed
CN-103998486-B Polycarbonate copolymer, coating liquid using same, and electrophotographic photoreceptor 出光兴产株式会社 2016-06-29 CN disclosed