Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28208747 | 0.97 | NQO2 (0.45) | NQO2MEN1KMT2AGAAMAOA | |
| SCHEMBL18407165 | 0.85 | APP (0.46) | NQO2KMT2AGAAMAOAKDM1A | |
| SCHEMBL28211601 | 0.76 | CYP1A2 (0.41) | CYP1A2BACE1 | |
| SCHEMBL13502280 | 0.73 | MAOA (0.65) | NQO2MEN1KMT2AGAAMAOA | |
| SCHEMBL27545880 | 0.71 | ADORA2A (0.41) | KMT2AGAACYP1A2KDM4EALDH1A1 | |
| SCHEMBL13696862 | 0.70 | ACHE (0.67) | NQO2KMT2AGAAMAOAKDM1A | |
| SCHEMBL27961718 | 0.70 | MAOA (0.67) | NQO2MEN1KMT2AGAAMAOA | |
| SCHEMBL15958501 | 0.70 | CYP1A2 (0.53) | MEN1KMT2ACYP1A2KDM4EALDH1A1 | |
| SCHEMBL28363563 | 0.70 | KMT2A (0.41) | NQO2MEN1KMT2AGAAMAOA | |
| SCHEMBL28361368 | 0.69 | ESR1 (0.64) | NQO2MEN1KMT2AGAAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503824-B | Acridine derivatives and preparation method thereof and as the purposes in anti-angiogenic medicaments | 广西中医药大学 | 2018-04-17 | — | — | CN | claimed |
| CN-105503824-A | Acridine derivative, preparation method thereof and application of acridine derivative as anti-angiogenesis drug | UNIV GUANGXI CHINESE MEDICINE | 2016-04-20 | — | — | CN | claimed |
| CN-105399726-A | 2-methyl-9-acridine (p-methylphenyl)-1,2,3-triazole and preparation method and application thereof | UNIV GUANGXI CHINESE MEDICINE | 2016-03-16 | — | — | CN | claimed |
| CN-105503824-B | Acridine derivatives and preparation method thereof and as the purposes in anti-angiogenic medicaments | 广西中医药大学 | 2018-04-17 | — | — | CN | disclosed |
| CN-105399726-B | 2 methyl, 9 acridine（P-methylphenyl）1,2,3 triazoles and its preparation method and application | 广西中医药大学 | 2018-04-17 | — | — | CN | disclosed |
| CN-105503824-A | Acridine derivative, preparation method thereof and application of acridine derivative as anti-angiogenesis drug | UNIV GUANGXI CHINESE MEDICINE | 2016-04-20 | — | — | CN | disclosed |
| CN-105399726-A | 2-methyl-9-acridine (p-methylphenyl)-1,2,3-triazole and preparation method and application thereof | UNIV GUANGXI CHINESE MEDICINE | 2016-03-16 | — | — | CN | disclosed |