Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.67 |
| ▸ | MAOB | P27338 | 1/20 | 0.67 |
| ▸ | NQO2 | P16083 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9593290 | 0.90 | LMNA (0.62) | MAOAMAOBNQO2LMNAKDM4E | |
| SCHEMBL9593514 | 0.89 | MAOA (0.67) | MAOAMAOBNQO2LMNAKDM4E | |
| SCHEMBL9595142 | 0.87 | LMNA (0.55) | MAOAMAOBNQO2LMNAKDM4E | |
| SCHEMBL11780381 | 0.82 | MAOA (0.75) | MAOAMAOBLMNAKDM4EALDH1A1 | |
| SCHEMBL22791812 | 0.82 | LMNA (0.50) | MAOAMAOBLMNAKDM4EALDH1A1 | |
| SCHEMBL15124839 | 0.82 | MAOA (0.82) | MAOAMAOBNQO2LMNAKDM4E | |
| SCHEMBL27889436 | 0.82 | MAOA (1.00) | MAOAMAOBNQO2LMNAKDM4E | |
| SCHEMBL455949 | 0.82 | MAOA (1.00) | MAOAMAOBNQO2LMNAKDM4E | |
| SCHEMBL9593843 | 0.81 | LMNA (0.53) | MAOAMAOBNQO2LMNAKDM4E | |
| SCHEMBL13502280 | 0.81 | MAOA (0.65) | MAOANQO2LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503824-B | Acridine derivatives and preparation method thereof and as the purposes in anti-angiogenic medicaments | 广西中医药大学 | 2018-04-17 | — | — | CN | claimed |
| CN-104327063-B | Acridine oxadiazole derivative, preparation method and uses thereof | 广西中医药大学 | 2017-01-11 | — | — | CN | claimed |
| CN-105503824-A | Acridine derivative, preparation method thereof and application of acridine derivative as anti-angiogenesis drug | UNIV GUANGXI CHINESE MEDICINE | 2016-04-20 | — | — | CN | claimed |
| CN-105476992-A | Application of 2-methoxy-9-acridine benzamido thiourea in preparation of acetylcholinesterase inhibitor | UNIV GUANGXI CHINESE MEDICINE | 2016-04-13 | — | — | CN | claimed |
| CN-105399726-A | 2-methyl-9-acridine (p-methylphenyl)-1,2,3-triazole and preparation method and application thereof | UNIV GUANGXI CHINESE MEDICINE | 2016-03-16 | — | — | CN | claimed |
| CN-104326979-B | 2-methyl-9-acridine (to methoxy benzamide base) thiocarbamide and its production and use | GUANGXI UNIVERSITY OF CHINESE MEDICINE (CN) | 2015-12-30 | — | — | CN | claimed |
| CN-104327063-A | Acridine oxadiazole derivative, preparation method and uses thereof | UNIV GUANGXI CHINESE MEDICINE | 2015-02-04 | — | — | CN | claimed |
| CN-104326979-A | 2-methyl-9-acridine(p-methoxy benzamido)thiourea, preparation method and uses thereof | UNIV GUANGXI CHINESE MEDICINE | 2015-02-04 | — | — | CN | claimed |
| CN-106045973-B | 4- amide groups benzimidazole acridine compound and its preparation method and application | 清华大学深圳研究生院 | 2019-03-22 | — | — | CN | disclosed |
| CN-105476992-B | Application of the 2- methoxyl group -9- acridine benzamido thiocarbamides in acetylcholinesterase inhibitor is prepared | 广西中医药大学 | 2018-07-06 | — | — | CN | disclosed |
| CN-105399726-B | 2 methyl, 9 acridine（P-methylphenyl）1,2,3 triazoles and its preparation method and application | 广西中医药大学 | 2018-04-17 | — | — | CN | disclosed |
| CN-105503824-B | Acridine derivatives and preparation method thereof and as the purposes in anti-angiogenic medicaments | 广西中医药大学 | 2018-04-17 | — | — | CN | disclosed |
| CN-104327063-B | Acridine oxadiazole derivative, preparation method and uses thereof | 广西中医药大学 | 2017-01-11 | — | — | CN | disclosed |
| CN-106045973-A | 4-Amidobenzoimidazolacridine compound and preparation method and application thereof | 清华大学深圳研究生院 | 2016-10-26 | — | — | CN | disclosed |
| CN-105476992-A | Application of 2-methoxy-9-acridine benzamido thiourea in preparation of acetylcholinesterase inhibitor | UNIV GUANGXI CHINESE MEDICINE | 2016-04-13 | — | — | CN | disclosed |
| CN-105399726-A | 2-methyl-9-acridine (p-methylphenyl)-1,2,3-triazole and preparation method and application thereof | UNIV GUANGXI CHINESE MEDICINE | 2016-03-16 | — | — | CN | disclosed |
| CN-104326979-B | 2-methyl-9-acridine (to methoxy benzamide base) thiocarbamide and its production and use | GUANGXI UNIVERSITY OF CHINESE MEDICINE (CN) | 2015-12-30 | — | — | CN | disclosed |
| CN-104326979-A | 2-methyl-9-acridine(p-methoxy benzamido)thiourea, preparation method and uses thereof | UNIV GUANGXI CHINESE MEDICINE | 2015-02-04 | — | — | CN | disclosed |
| CN-104327063-A | Acridine oxadiazole derivative, preparation method and uses thereof | UNIV GUANGXI CHINESE MEDICINE | 2015-02-04 | — | — | CN | disclosed |
| CN-103896918-A | Compound as well as preparation method and application thereof | UNIV TSINGHUA GRADUATE SCHOOL | 2014-07-02 | — | — | CN | disclosed |