Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28462617 | 0.93 | SOAT2 (0.46) | HPGDLMNATSHRFAAHCES1 | |
| SCHEMBL38728 | 0.88 | LMNA (0.46) | HDAC3SMN1; SMN2LMNAFAAHCES1 | |
| SCHEMBL302694 | 0.86 | TDP1 (0.47) | SMN1; SMN2LMNATSHRFAAHCES1 | |
| SCHEMBL5206775 | 0.86 | TDP1 (0.47) | SMN1; SMN2LMNATSHRFAAHCES1 | |
| SCHEMBL302928 | 0.86 | TDP1 (0.47) | SMN1; SMN2LMNATSHRFAAHCES1 | |
| SCHEMBL303164 | 0.86 | TDP1 (0.47) | SMN1; SMN2LMNATSHRFAAHCES1 | |
| SCHEMBL304116 | 0.86 | TDP1 (0.47) | SMN1; SMN2LMNATSHRFAAHCES1 | |
| SCHEMBL302971 | 0.86 | TDP1 (0.47) | SMN1; SMN2LMNATSHRFAAHCES1 | |
| SCHEMBL303521 | 0.86 | TDP1 (0.47) | SMN1; SMN2LMNATSHRFAAHCES1 | |
| SCHEMBL139446 | 0.86 | TDP1 (0.47) | SMN1; SMN2LMNATSHRFAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555270-A | Pharmaceutical composition for treatment and/or prevention of lung diseases | UBE INDUSTRIES | 2016-05-04 | — | — | CN | disclosed |
| CN-105308023-A | substituted biaryl compounds | UBE INDUSTRIES | 2016-02-03 | — | — | CN | disclosed |