SCHEMBL28054680

SCHEMBL28054680

O=S(=O)(c1ccc(-n2cnnc2)cc1)c1ccc(-n2cnnc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.47
CYP1A2 P05177 1/20 0.47
QPCT Q16769 1/20 0.46
HTR6 P50406 3/20 0.41
CYP3A4 P08684 2/20 0.41
TSHR P16473 2/20 0.41
LMNA P02545 2/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPK1 P28482 1/20 0.41
MPO P05164 1/20 0.41
GAA P10253 1/20 0.41
PKM P14618 2/20 0.39
RXFP1 Q9HBX9 1/20 0.38
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5487533 0.83 CHRNA7 (0.49) CYP2C9CYP1A2TSHRLMNAALDH1A1
SCHEMBL28002115 0.80 CYP1A2 (0.64) CYP2C9CYP1A2QPCTCYP3A4TSHR
SCHEMBL7660833 0.75 CYP1A2 (0.50) CYP2C9CYP1A2QPCTTSHRLMNA
SCHEMBL7660151 0.75 CYP1A2 (0.38) CYP2C9CYP1A2QPCTLMNAALDH1A1
Hydrochloric Acid SCHEMBL7660837 0.73 CYP1A2 (0.47) CYP2C9CYP1A2QPCTTSHRLMNA
Hydrochloric Acid SCHEMBL7660158 0.73 QPCT (0.39) CYP2C9CYP1A2QPCTTSHRLMNA
SCHEMBL2511973 0.70 KCNJ1 (0.53) CYP2C9CYP1A2QPCTALDH1A1MAPK1
SCHEMBL1186988 0.69 ENPP2 (0.56) CYP2C9CYP1A2QPCTCYP3A4LMNA
SCHEMBL6518759 0.69 CYP2C9 (0.58) CYP2C9CYP1A2QPCTTSHRLMNA
SCHEMBL21923049 0.69 CYP1A2 (0.52) CYP2C9CYP1A2QPCTLMNAMPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105669570-A Tetraminosulfinylbistriazolyl copper complex monocrystal, and preparation method and application thereof 天津师范大学 2016-06-15 CN claimed
CN-105503911-A Tetraamino sulfoxide bitriazole zinc complex single crystal and preparation method and application thereof UNIV TIANJIN 2016-04-20 CN claimed
CN-105669570-A Tetraminosulfinylbistriazolyl copper complex monocrystal, and preparation method and application thereof 天津师范大学 2016-06-15 CN disclosed
CN-105669570-A Tetraminosulfinylbistriazolyl copper complex monocrystal, and preparation method and application thereof 天津师范大学 2016-06-15 CN disclosed
CN-105503911-A Tetraamino sulfoxide bitriazole zinc complex single crystal and preparation method and application thereof UNIV TIANJIN 2016-04-20 CN disclosed
CN-105503911-A Tetraamino sulfoxide bitriazole zinc complex single crystal and preparation method and application thereof UNIV TIANJIN 2016-04-20 CN disclosed