Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 17/20 | 0.48 |
| ▸ | CA12 | O43570 | 15/20 | 0.48 |
| ▸ | CA9 | Q16790 | 15/20 | 0.48 |
| ▸ | CA1 | P00915 | 15/20 | 0.48 |
| ▸ | CA5A | P35218 | 4/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.46 |
| ▸ | CA7 | P43166 | 4/20 | 0.46 |
| ▸ | CA6 | P23280 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28054680 | 0.83 | CYP2C9 (0.47) | TSHRALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL4408673 | 0.77 | CHRNA7 (0.76) | CHRNA7CA2CA12CA9CA1 | |
| SCHEMBL2771870 | 0.77 | CA2 (0.56) | CA2CA12CA9CA1CA5A | |
| SCHEMBL28002115 | 0.76 | CYP1A2 (0.64) | CA12CA9TSHRLMNACYP1A2 | |
| SCHEMBL202948 | 0.74 | CA2 (0.81) | CA2CA12CA9CA1CA5A | |
| SCHEMBL18109146 | 0.73 | LMNA (0.67) | CA2CA12CA9CA1CA5A | |
| SCHEMBL7660151 | 0.72 | CYP1A2 (0.38) | TDP1ALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL7660833 | 0.72 | CYP1A2 (0.50) | TSHRTDP1ALDH1A1LMNACYP1A2 | |
| SCHEMBL14204073 | 0.71 | PTGS2 (0.43) | CA2CA12CA9CA1CA5A | |
| SCHEMBL1352015 | 0.70 | MAPT (0.56) | USP2TSHRTDP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183320-B2 | Benzoylsulfonamides and sulfonylbenzamidines for use as antitumour agents | ELI LILLY AND COMPANY (US) | 2007-02-27 | — | — | US | disclosed |