Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | PPOX | P50336 | 1/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
| ▸ | MERTK | Q12866 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | DTYMK | P23919 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28447405 | 0.88 | KMT2A (0.40) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL29596381 | 0.83 | HTT (0.49) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL28256503 | 0.83 | HTT (0.49) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL28256429 | 0.82 | HPSE (0.64) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL2821186 | 0.79 | HPSE (0.56) | MEN1KMT2ATTRHPSEEPAS1 | |
| SCHEMBL28054763 | 0.79 | HSPB1 (0.58) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL28054738 | 0.79 | HPSE (0.50) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL9543906 | 0.78 | MEN1 (0.56) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL28054740 | 0.77 | KMT2A (0.53) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL28456608 | 0.76 | TDP1 (0.49) | MEN1KMT2ATDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693634-B | Compound and application thereof | 清华大学 | 2018-12-11 | — | — | CN | disclosed |
| CN-105693634-A | Compound and application thereof | 清华大学 | 2016-06-22 | — | — | CN | disclosed |