Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | PPOX | P50336 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28054855 | 0.88 | MEN1 (0.46) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL28625744 | 0.83 | MAPT (0.51) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL28897949 | 0.82 | HPSE (0.47) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL28440598 | 0.81 | LMNA (0.40) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL28448999 | 0.79 | MAPT (0.45) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL28456608 | 0.78 | TDP1 (0.49) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL28256503 | 0.77 | HTT (0.49) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL29596381 | 0.77 | HTT (0.49) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL28446764 | 0.75 | ALDH1A1 (0.41) | KMT2AMEN1TDP1TTRPPOX | |
| SCHEMBL28448772 | 0.74 | LMNA (0.40) | KMT2AMEN1TDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831614-B | Substituted benzodiazacyclo compound and its preparation method and use | 清华大学 | 2020-07-28 | — | — | CN | disclosed |