Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | PPOX | P50336 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | DTYMK | P23919 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29596381 | 1.00 | HTT (0.49) | HTTPOLBHPSEKMT2AMEN1 | |
| SCHEMBL28054907 | 0.89 | POLB (0.41) | HTTPOLBHPSEKMT2AMEN1 | |
| SCHEMBL30616305 | 0.87 | ALDH1A1 (0.47) | HTTPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL28054855 | 0.83 | MEN1 (0.46) | HPSEKMT2AMEN1TDP1TTR | |
| SCHEMBL28256429 | 0.82 | HPSE (0.64) | HPSEKMT2AMEN1TDP1TTR | |
| SCHEMBL28054740 | 0.82 | KMT2A (0.53) | HTTPOLBHPSEKMT2AMEN1 | |
| SCHEMBL28054738 | 0.82 | HPSE (0.50) | HTTPOLBHPSEKMT2AMEN1 | |
| SCHEMBL28054674 | 0.80 | ALDH1A1 (0.46) | KMT2AMEN1TDP1TSHRALDH1A1 | |
| SCHEMBL28054763 | 0.79 | HSPB1 (0.58) | HTTHPSEKMT2AMEN1TDP1 | |
| SCHEMBL28625744 | 0.79 | MAPT (0.51) | HTTHPSEKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693634-B | Compound and application thereof | 清华大学 | 2018-12-11 | — | — | CN | disclosed |