Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | RXRG | P48443 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28781835 | 0.88 | MAOB (0.43) | RAB9AMAOBNPC1NR4A2APP | |
| SCHEMBL9401075 | 0.79 | IDH1 (0.41) | RAB9ADRD2DRD4SMN1; SMN2MAOB | |
| SCHEMBL2454046 | 0.76 | KCNH2 (0.46) | RAB9AMEN1KMT2ASMN1; SMN2MAOB | |
| SCHEMBL195811 | 0.74 | S1PR4 (0.33) | — | |
| SCHEMBL27413501 | 0.74 | MAOB (0.43) | RAB9ADRD2DRD4SMN1; SMN2MAOB | |
| SCHEMBL2154106 | 0.73 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL5672571 | 0.72 | APP (0.44) | RAB9ASMN1; SMN2MAOBRXRARXRB | |
| SCHEMBL11959143 | 0.69 | MAOB (0.72) | RAB9AMAOBRXRARXRBRXRG | |
| SCHEMBL1691558 | 0.69 | CYP1A2 (0.44) | RAB9AMEN1KMT2ASMN1; SMN2MAOB | |
| SCHEMBL10414133 | 0.69 | KCNH2 (0.42) | RAB9ADRD2DRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102264693-B | The acrylamide derivative of inhibitor is changed as mitochondrial permeability | CONGENIA S.R.L. (IT) | 2016-01-27 | — | — | CN | disclosed |