Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2306843 | 0.80 | IDH1 (0.47) | IDH1KCNH2DRD2DRD4MAOB | |
| SCHEMBL28055080 | 0.79 | RAB9A (0.42) | KCNH2DRD2DRD4MAOBPOLB | |
| SCHEMBL2454046 | 0.76 | KCNH2 (0.46) | KCNH2MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5111421 | 0.76 | ACHE (0.31) | — | |
| SCHEMBL27603316 | 0.74 | ACHE (0.30) | — | |
| SCHEMBL2852601 | 0.73 | CALM1 (0.41) | IDH1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8750627 | 0.71 | MAOA (0.37) | KCNH2MAOBNPC1RAB9ATDP1 | |
| SCHEMBL17818217 | 0.71 | ACHE (0.33) | — | |
| SCHEMBL11417292 | 0.71 | ACHE (0.33) | KDM4E | |
| SCHEMBL21986317 | 0.69 | LTA4H (0.41) | MAOBSMN1; SMN2TDP1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356908-A | Agriculture | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-10-18 | — | — | US | disclosed |
| US-5223523-A | Agriculture | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-29 | — | — | US | disclosed |
| US-4957933-A | Fungicidal oxazolidinones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-09-18 | — | — | US | disclosed |