Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25270 | 0.97 | QPCT (0.38) | QPCTHSD17B10NFKB1QPCTLCYP19A1 | |
| Potassium Ion SCHEMBL28275079 | 0.92 | HSD17B10 (0.35) | QPCTHSD17B10NFKB1QPCTLCYP19A1 | |
| SCHEMBL16133373 | 0.88 | FBP1 (0.36) | QPCTHSD17B10NFKB1QPCTLCYP19A1 | |
| SCHEMBL12490284 | 0.81 | FAAH (0.40) | QPCTHSD17B10NFKB1QPCTLCYP19A1 | |
| SCHEMBL7812595 | 0.81 | QPCT (0.38) | QPCTHSD17B10NFKB1QPCTLCYP19A1 | |
| Imidazole SCHEMBL9377131 | 0.80 | ALDH1A1 (0.48) | QPCTHSD17B10NFKB1QPCTLALDH1A1 | |
| SCHEMBL255373 | 0.79 | — | — | |
| SCHEMBL13685027 | 0.79 | — | — | |
| SCHEMBL13003050 | 0.78 | FAAH (0.35) | HSD17B10NFKB1CYP19A1CYP1A2CYP3A4 | |
| SCHEMBL8296674 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214484-B | Pyrrolo-[2,3-b] pyridine replaced as the heteroaryl of Janus inhibitors of kinases and pyrrolo-[2,3-b] pyrimidine | 因塞特控股公司 | 2016-07-06 | — | — | CN | disclosed |