Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CBR1 | P16152 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL665598 | 1.00 | HSD17B10 (0.61) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| Water SCHEMBL7522925 | 0.98 | HSD17B10 (0.58) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL339112 | 0.89 | HSD17B10 (0.65) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL21177792 | 0.87 | HSD17B10 (0.52) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL29624840 | 0.87 | AHR (0.64) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL464507 | 0.87 | AHR (0.64) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL13907547 | 0.85 | TSHR (0.50) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| Ether SCHEMBL2015800 | 0.84 | TSHR (0.45) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL11090674 | 0.81 | HSD17B10 (0.56) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL16720300 | 0.80 | HSD17B10 (0.45) | HSD17B10TSHRALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105407729-A | Compositions and methods comprising a polyamine | CURZA GLOBAL LLC | 2016-03-16 | — | — | CN | disclosed |