Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788705 | 0.76 | MEN1 (0.45) | MEN1KMT2ASLC6A2SLC6A4FABP4 | |
| Hydrochloric Acid SCHEMBL3247223 | 0.75 | MEN1 (0.44) | MEN1KMT2ASLC6A2SLC6A4FABP4 | |
| SCHEMBL27559450 | 0.74 | MEN1 (0.51) | MEN1KMT2ASLC6A2FABP4KDM4E | |
| SCHEMBL26185613 | 0.74 | HTR2A (0.54) | HTR6 | |
| SCHEMBL8089258 | 0.73 | MEN1 (0.50) | MEN1KMT2AFABP4KDM4ENQO2 | |
| SCHEMBL13107371 | 0.72 | MEN1 (0.41) | MEN1KMT2ASLC6A2SLC6A4FABP4 | |
| SCHEMBL28670259 | 0.72 | MEN1 (0.45) | MEN1KMT2ASLC6A2FABP4KDM4E | |
| SCHEMBL27818053 | 0.70 | MEN1 (0.44) | MEN1KMT2ASLC6A2SLC6A4FABP4 | |
| SCHEMBL8927744 | 0.70 | MEN1 (0.46) | MEN1KMT2ASLC6A2SLC6A4FABP4 | |
| SCHEMBL28805445 | 0.70 | GPR3 (0.41) | MEN1KMT2AFABP4KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272967-A | Triazine epidermal growth factor acceptor inhibitor and application thereof | NANJING SANHOME PHARMACEUTICAL CO LTD | 2016-01-27 | — | — | CN | disclosed |