Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 2/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28195676 | 0.88 | MAPT (0.45) | TRPV1SCN2AKIF11CCNB2CDK1 | |
| SCHEMBL28646823 | 0.86 | ALDH1A1 (0.44) | IDO1SCN2AKIF11CCNB2CDK1 | |
| SCHEMBL28195673 | 0.86 | KIF11 (0.33) | TRPV1SCN2AKIF11CCNB2CDK1 | |
| SCHEMBL28627573 | 0.86 | MAPT (0.44) | TRPV1IDO1SCN2AKIF11CCNB2 | |
| SCHEMBL28195733 | 0.86 | GCGR (0.39) | TRPV1IDO1SCN2AKIF11CCNB2 | |
| SCHEMBL28195066 | 0.86 | SCN2A (0.43) | IDO1SCN2AKIF11MPIALDH1A1 | |
| SCHEMBL28195679 | 0.85 | IDO1 (0.35) | TRPV1IDO1SCN2AKIF11MPI | |
| SCHEMBL28195019 | 0.84 | TRPA1 (0.38) | TRPV1KIF11CCNB2CDK1CCNB1 | |
| SCHEMBL28195670 | 0.83 | KIF11 (0.51) | KIF11ALDH1A1MAPTGCGRMAPK14 | |
| SCHEMBL28195054 | 0.83 | NPBWR1 (0.39) | IDO1KIF11HTR3EHTR3BPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107629022-B | Antibacterial synergist and preparation method and application thereof | 上海医药工业研究院 | 2024-11-12 | — | — | CN | disclosed |
| CN-107625766-B | Application of thiazole compound as antibacterial synergist | 上海医药工业研究院 | 2021-08-31 | — | — | CN | disclosed |
| CN-107629023-A | A kind of new fragrant imido grpup thiazole compound, preparation method and use | 华东理工大学 | 2018-01-26 | — | — | CN | disclosed |
| CN-107625766-A | A kind of thiazole compound is used as the purposes of Trimethoprim | 上海医药工业研究院 | 2018-01-26 | — | — | CN | disclosed |
| CN-107629022-A | A kind of Trimethoprim and its preparation method and purposes | 上海医药工业研究院 | 2018-01-26 | — | — | CN | disclosed |