SCHEMBL28055655

SCHEMBL28055655

O=c1ccc2ccc(-c3cccc(O)c3O)cc2o1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 3/20 0.54
CA9 Q16790 8/20 0.51
MCL1 Q07820 7/20 0.51
CA12 O43570 7/20 0.51
GAA P10253 5/20 0.51
KDM4E B2RXH2 5/20 0.51
HPGD P15428 5/20 0.51
HSD17B10 Q99714 5/20 0.51
CA1 P00915 5/20 0.51
AKR1B1 P15121 4/20 0.51
ALDH1A1 P00352 4/20 0.51
TDP1 Q9NUW8 4/20 0.51
GLA P06280 3/20 0.51
CASP1 P29466 3/20 0.51
CASP7 P55210 3/20 0.51
ERAP1 Q9NZ08 3/20 0.51
CYP3A4 P08684 3/20 0.51
MAPT P10636 3/20 0.51
ALOX15 P16050 3/20 0.51
LMNA P02545 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9174598 0.85 PGR (0.51) PGRCA9MCL1CA12GAA
SCHEMBL19317202 0.77 CA12 (0.53) PGRCA9MCL1CA12GAA
SCHEMBL5008339 0.75 CYP19A1 (0.51) PGRCA9MCL1CA12GAA
SCHEMBL1706854 0.74 PGR (0.69) PGRCA9MCL1CA12GAA
SCHEMBL19211556 0.72 HDAC4 (0.66) MCL1CYP1A2HDAC4HDAC2HDAC8
SCHEMBL15842362 0.72 PGR (0.77) PGRCA9MCL1CA12GAA
Hydrogen Sulfide SCHEMBL27593454 0.72 PGR (0.56) PGRCA9MCL1CA12GAA
SCHEMBL31676674 0.71 CA12 (0.73) PGRCA9MCL1CA12GAA
SCHEMBL9973586 0.70 HPGD (0.52) KDM4EHPGDHSD17B10CA1AKR1B1
Coumarin SCHEMBL7644084 0.70 CA12 (0.67) PGRCA9MCL1CA12GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101611148-B Water-soluble phenolic derivatives for cosmetic and therapeutic applications on the skin LIBRAGEN (FR) 2016-03-16 CN disclosed