Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.69 |
| ▸ | CA9 | Q16790 | 9/20 | 0.62 |
| ▸ | CA12 | O43570 | 7/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | GLA | P06280 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | CASP1 | P29466 | 3/20 | 0.62 |
| ▸ | CASP7 | P55210 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | BCHE | P06276 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18788576 | 0.82 | PGR (0.52) | PGRCA9CA12MCL1AKR1B1 | |
| SCHEMBL30108452 | 0.79 | MIF (0.74) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL1706856 | 0.79 | MIF (0.74) | KDM4EALDH1A1GLAGAAHPGD | |
| Esculetin SCHEMBL24641 | 0.77 | CA9 (1.00) | PGRCA9CA12MCL1AKR1B1 | |
| Esculetin SCHEMBL29569228 | 0.77 | CA9 (1.00) | PGRCA9CA12MCL1AKR1B1 | |
| Esculetin SCHEMBL6867015 | 0.77 | CA9 (1.00) | PGRCA9CA12MCL1AKR1B1 | |
| Esculetin SCHEMBL8718947 | 0.76 | CA9 (0.79) | PGRCA9CA12MCL1AKR1B1 | |
| SCHEMBL2355820 | 0.76 | LMNA (0.77) | CA9CA12AKR1B1KDM4EALDH1A1 | |
| SCHEMBL30108485 | 0.76 | LMNA (0.77) | CA9CA12AKR1B1KDM4EALDH1A1 | |
| Esculetin SCHEMBL1736697 | 0.76 | CA9 (0.96) | PGRCA9CA12MCL1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828407-B2 | Water soluble and activable phenolic derivatives with dermocosmetic and therapeutic applications and process for preparing said derivatives | LIBRAGEN (FR) | 2017-11-28 | — | — | US | claimed |
| US-20140088030-A1 | WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES | LIBRAGEN (FR) | 2014-03-27 | — | — | US | claimed |
| EP-2027279-B1 | Phenolic compounds with cosmetic and therapeutic applications | LIBRAGEN (FR) | 2012-04-18 | — | — | EP | claimed |
| EP-2027279-A2 | WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES | Libragen (FR) | 2009-02-25 | — | — | EP | claimed |
| WO-2007144368-A2 | WATER SOLUBLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS | LIBRAGEN (FR) | 2007-12-21 | — | — | WO | claimed |
| CN-105838758-B | Water-soluble phenolic derivatives for cosmetic and therapeutic applications on the skin | 利布莱根公司 | 2020-03-06 | — | — | CN | disclosed |
| US-9828407-B2 | Water soluble and activable phenolic derivatives with dermocosmetic and therapeutic applications and process for preparing said derivatives | LIBRAGEN (FR) | 2017-11-28 | — | — | US | disclosed |
| CN-105838758-A | Water soluble phenolics derivatives with dermocosmetic and therapeutic applications | 利布莱根公司 | 2016-08-10 | — | — | CN | disclosed |
| CN-101611148-B | Water-soluble phenolic derivatives for cosmetic and therapeutic applications on the skin | LIBRAGEN (FR) | 2016-03-16 | — | — | CN | disclosed |
| US-20140088030-A1 | WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES | LIBRAGEN (FR) | 2014-03-27 | — | — | US | disclosed |
| US-20090233876-A1 | Water Soluble and Activable Phenolics Derivatives with Dermocosmetic and Therapeutic Applications and Process for Preparing Said Derivatives | LIBRAGEN (FR) | 2009-09-17 | — | — | US | disclosed |
| EP-2027279-A2 | WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES | Libragen (FR) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007144368-A2 | WATER SOLUBLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS | LIBRAGEN (FR) | 2007-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233876-A1 | Water Soluble and Activable Phenolics Derivatives with Dermocosmetic and Therapeutic Applications and Process for Preparing Said Derivatives | UGGT1, TYR, LCT | PGR 2966/4885CA9 3628/4885CA12 4097/4885 |
| US-20140088030-A1 | WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES | UGGT1, TYR, G6PD | PGR 2573/4885CA9 3760/4885CA12 4200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.