SCHEMBL9973586

SCHEMBL9973586

Oc1cccc(-c2cccc(-c3cccc(O)c3O)c2)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.52
HSD17B10 Q99714 5/20 0.52
ALDH1A1 P00352 4/20 0.52
ALOX15 P16050 4/20 0.52
TDP1 Q9NUW8 4/20 0.52
RECQL P46063 3/20 0.52
LMNA P02545 2/20 0.52
ADAMTS4 O75173 1/20 0.52
EGFR P00533 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
FYN P06241 1/20 0.52
MMP2 P08253 1/20 0.52
MMP9 P14780 1/20 0.52
MMP8 P22894 1/20 0.52
CA6 P23280 1/20 0.52
CDK2 P24941 1/20 0.52
MMP12 P39900 1/20 0.52
ADAMTS5 Q9UNA0 1/20 0.52
BCL2L1 Q07817 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13368747 0.93 HPGD (0.60) HPGDHSD17B10ALDH1A1ALOX15TDP1
SCHEMBL10338434 0.91 HDAC4 (0.53) HPGDHSD17B10ALDH1A1ALOX15TDP1
SCHEMBL8778337 0.91 HDAC4 (0.53) HPGDHSD17B10ALDH1A1ALOX15TDP1
SCHEMBL23290116 0.89 HSD17B1 (0.54) HPGDHSD17B10ALDH1A1ALOX15TDP1
SCHEMBL16674077 0.88 TRPA1 (0.59) HPGDHSD17B10ALDH1A1ALOX15TDP1
SCHEMBL16768982 0.88 TRPA1 (0.43) HPGDHSD17B10ALDH1A1ALOX15TDP1
Bicarbonate SCHEMBL9704219 0.86 HDAC4 (0.53) HPGDHSD17B10ALDH1A1BCL2L1HSD17B14
SCHEMBL29365218 0.85 ALDH1A1 (0.68) HPGDHSD17B10ALDH1A1ALOX15TDP1
SCHEMBL94298 0.85 ALDH1A1 (0.68) HPGDHSD17B10ALDH1A1ALOX15TDP1
SCHEMBL9742510 0.85 ALOX15 (0.50) HPGDHSD17B10ALDH1A1ALOX15TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019173595-A2 FUNCTIONAL MOLECULES AND OTHER STRUCTURAL CARBON-BASED MOLECULES WITH RIGID BACKBONES AND KINKED SEGMENTS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2019-09-12 WO disclosed
US-20190276952-A1 FUNCTIONAL MOLECULES AND OTHER STRUCTURAL CARBON-BASED MOLECULES WITH RIGID BACKBONES AND KINKED SEGMENTS EXXONMOBIL RES & ENG CO (US) 2019-09-12 US disclosed
US-20160367948-A1 CROSSLINKED POLYMER, METHOD FOR PRODUCING THE SAME, MOLECULAR SIEVE COMPOSITION AND MATERIAL SEPARATION MEMBRANES KYOTO UNIVERSITY (JP) 2016-12-22 US disclosed
US-20160367948-A1 CROSSLINKED POLYMER, METHOD FOR PRODUCING THE SAME, MOLECULAR SIEVE COMPOSITION AND MATERIAL SEPARATION MEMBRANES KYOTO UNIVERSITY (JP) 2016-12-22 US disclosed
US-9522364-B2 Treated mixed matrix polymeric membranes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-12-20 US disclosed
US-9522364-B2 Treated mixed matrix polymeric membranes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-12-20 US disclosed
US-9492785-B2 UV and thermally treated polymeric membranes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-11-15 US disclosed
US-9492785-B2 UV and thermally treated polymeric membranes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-11-15 US disclosed
US-20160263531-A1 PLASMA-TREATED POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-15 US disclosed
US-20160263531-A1 PLASMA-TREATED POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-15 US disclosed
US-8056732-B2 Microporous polymer material THE UNIVERSITY OF MANCHESTER (GB) 2011-11-15 US disclosed
US-20110190409-A1 LADDER POLYMERS WITH INSTRINSIC MICROPOROSITY AND PROCESS FOR PRODUCTION THEREOF NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2011-08-04 US disclosed
US-20100304112-A1 MICROPOROUS POLYMER MATERIAL THE UNIVERSITY OF MANCHESTER (GB) 2010-12-02 US disclosed
US-7758751-B1 UV-cross-linked membranes from polymers of intrinsic microporosity for liquid separations UOP LLC (US) 2010-07-20 US disclosed
US-7704751-B2 Polymeric fluorescent chemical sensor 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-04-27 US disclosed
US-7704751-B2 Polymeric fluorescent chemical sensor 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-04-27 US disclosed
US-7690514-B2 Microporous polymer material THE UNIVERSITY OF MANCHESTER (GB) 2010-04-06 US disclosed
WO-2008036524-A1 FLUORESCENT CHEMICAL SENSOR 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-03-27 WO disclosed
US-20080070320-A1 FLUORESCENT CHEMICAL SENSOR 3M INNOVATIVE PROPERTIES COMPANY 2008-03-20 US disclosed
US-20080070320-A1 FLUORESCENT CHEMICAL SENSOR 3M INNOVATIVE PROPERTIES COMPANY 2008-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110190409-A1 LADDER POLYMERS WITH INSTRINSIC MICROPOROSITY AND PROCESS FOR PRODUCTION THEREOF CCR3, CNOT9, AR HPGD 4274/4885HSD17B10 1437/4885ALDH1A1 1922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.