Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.58 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | WEE1 | P30291 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.45 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.40 |
| ▸ | CFD | P00746 | 3/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572315 | 0.85 | BACE1 (0.49) | ENPP2BACE1CHEK1WEE1FGFR1 | |
| SCHEMBL28060034 | 0.84 | ABAT (0.56) | ENPP2BACE1ABATPELI1DRD2 | |
| Hydrochloric Acid SCHEMBL6780409 | 0.83 | BACE1 (0.47) | ENPP2BACE1CHEK1WEE1FGFR1 | |
| SCHEMBL11509337 | 0.83 | THRA (0.49) | BACE1FGFR1PELI1ALOX5MMP3 | |
| SCHEMBL2450409 | 0.82 | ALDH1A1 (0.52) | ENPP2BACE1FGFR1FGFR2FGFR3 | |
| SCHEMBL13867738 | 0.81 | PELI1 (0.53) | BACE1PELI1ALOX5ESR2NPC1 | |
| SCHEMBL2948809 | 0.80 | ENPP2 (0.76) | ENPP2ABATFGFR1FGFR2FGFR3 | |
| SCHEMBL28241992 | 0.79 | ENPP2 (0.48) | ENPP2BACE1FGFR1FGFR2FGFR3 | |
| SCHEMBL28241991 | 0.79 | ENPP2 (0.53) | ENPP2CHEK1WEE1ABATFGFR1 | |
| SCHEMBL17754365 | 0.79 | PELI1 (0.61) | BACE1PELI1ALOX5ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103435804-B | Containing polybenzimidazole and preparation method thereof and the application of side base and ehter bond | JILIN UNIVERSITY (CN) | 2016-02-17 | — | — | CN | disclosed |