Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394896 | 0.83 | MAPT (1.00) | ALDH1A1MAPTCYP1A2TYMSSMN1; SMN2 | |
| Quinoline SCHEMBL27721275 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1CYP1A2HTT | |
| Quinoline SCHEMBL27554403 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1CYP1A2HTT | |
| Quinoline SCHEMBL27720870 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MAPTPOLBPDE10AL3MBTL1 | |
| Quinoline SCHEMBL27724871 | 0.76 | POLB (0.49) | ALDH1A1MAPTPOLBPDE10AL3MBTL1 | |
| Quinoline SCHEMBL28062786 | 0.76 | POLB (0.49) | ALDH1A1MAPTPOLBPDE10AL3MBTL1 | |
| SCHEMBL31110031 | 0.75 | MAPT (0.82) | ALDH1A1MAPTCYP1A2HTTTYMS | |
| SCHEMBL28354663 | 0.73 | MAPT (0.53) | ALDH1A1MAPTPOLBPDE10AL3MBTL1 | |
| Quinoline SCHEMBL27814435 | 0.72 | POLB (0.64) | ALDH1A1MAPTPOLBPDE10AL3MBTL1 | |
| Quinoline SCHEMBL28176263 | 0.72 | ALDH1A1 (0.57) | ALDH1A1MAPTPOLBPDE10AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105530932-A | Primary carboxamides as BIK inhibitors | ABBVIE INC | 2016-04-27 | — | — | CN | disclosed |