Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL376278 | 0.84 | PNMT (0.47) | PDE10AALDH1A1TDP1MAPTTSHR | |
| Quinoline SCHEMBL27720870 | 0.83 | ALDH1A1 (0.40) | POLBPDE10ANCOA1NCOA3ALDH1A1 | |
| 2-Chloropyridine SCHEMBL9390160 | 0.81 | TDP1 (0.41) | POLBPDE10AALDH1A1NPC1RAB9A | |
| Quinoline SCHEMBL28062786 | 0.80 | POLB (0.49) | POLBPDE10ANCOA1NCOA3ALDH1A1 | |
| Quinoline SCHEMBL27814435 | 0.79 | POLB (0.64) | POLBPDE10ANCOA1NCOA3ALDH1A1 | |
| Quinoline SCHEMBL28055899 | 0.76 | ALDH1A1 (0.68) | POLBPDE10ANCOA1NCOA3ALDH1A1 | |
| Quinoline SCHEMBL9110913 | 0.76 | POLB (0.84) | POLBPDE10ANCOA1NCOA3ALDH1A1 | |
| Quinoline SCHEMBL9110228 | 0.76 | PDE10A (0.81) | POLBPDE10ANCOA1NCOA3ALDH1A1 | |
| SCHEMBL10400093 | 0.75 | SRC (0.47) | PDE10AALDH1A1KDM4EMEN1KMT2A | |
| Quinoline SCHEMBL28318176 | 0.75 | POLB (0.46) | POLBPDE10ANCOA1NCOA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110183549-A | Light/pH double responsiveness sodium alginate derivative and the preparation method and application thereof | 湖北三江航天江河化工科技有限公司 | 2019-08-30 | — | — | CN | disclosed |
| CN-108473984-A | The group of nucleic acid bar code for analyzing nucleic acid associated with individual cells is combined | 阿特雷卡公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-106719630-A | Optical Response controlled release nanometer pesticidal preparations and its preparation method and application | 武汉理工大学 | 2017-05-31 | — | — | CN | disclosed |
| CN-106719617-A | A kind of optical Response pesticide nano micella and preparation method thereof and purposes | 武汉理工大学 | 2017-05-31 | — | — | CN | disclosed |
| CN-101321878-B | Non-fluorescent energy transfer | HOFFMANN LA ROCHE | 2013-03-27 | — | — | CN | disclosed |
| CN-101321878-A | Non-fluorescent energy transfer | ROCHE MOLECULAR SYSTEMS INC (CH) | 2008-12-10 | — | — | CN | disclosed |