Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1509290 | 0.83 | HSD17B10 (0.54) | HSD17B10TDP1ALDH1A1POLBTSHR | |
| SCHEMBL28056012 | 0.83 | TSHR (0.55) | HSD17B10TDP1ALDH1A1POLBTSHR | |
| Ammonia Solution, Strong SCHEMBL28268609 | 0.82 | HSD17B10 (0.52) | HSD17B10TDP1ALDH1A1POLBTSHR | |
| SCHEMBL27651310 | 0.82 | HSD17B10 (0.52) | HSD17B10TDP1ALDH1A1POLBTSHR | |
| Phosphine SCHEMBL28283987 | 0.82 | HSD17B10 (0.52) | HSD17B10TDP1ALDH1A1POLBTSHR | |
| SCHEMBL31195404 | 0.80 | HSD17B10 (0.50) | HSD17B10TDP1ALDH1A1POLBTSHR | |
| SCHEMBL11791524 | 0.80 | HSD17B10 (0.50) | HSD17B10TDP1ALDH1A1POLBTSHR | |
| SCHEMBL626777 | 0.80 | HSD17B10 (0.50) | HSD17B10TDP1ALDH1A1POLBTSHR | |
| SCHEMBL29669355 | 0.80 | HSD17B10 (0.50) | HSD17B10TDP1ALDH1A1POLBTSHR | |
| SCHEMBL304541 | 0.79 | HSD17B10 (0.48) | HSD17B10TDP1ALDH1A1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574094-B | Indolone derivatives and pharmaceutical use thereof | 成都大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-112574094-A | Indolone derivatives and pharmaceutical use thereof | 成都大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-105392557-A | Adsorbent and analysis system using same | HITACHI HIGH TECH CORP | 2016-03-09 | — | — | CN | disclosed |