Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515530 | 0.84 | TSHR (0.43) | TSHRGPR35TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28055935 | 0.83 | HSD17B10 (0.50) | TSHRGPR35TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2788910 | 0.81 | TSHR (0.53) | TSHRGPR35TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11323992 | 0.78 | GPR35 (0.58) | TSHRGPR35TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL118464 | 0.76 | TSHR (0.71) | TSHRGPR35TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1926046 | 0.76 | TSHR (0.71) | TSHRGPR35TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8811691 | 0.76 | TSHR (0.47) | TSHRGPR35TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11175107 | 0.75 | TSHR (0.46) | TSHRGPR35TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL414469 | 0.75 | ALDH3A1 (0.51) | TSHRGPR35TDP1SMN1; SMN2ALDH1A1 | |
| Methylamine SCHEMBL28414354 | 0.74 | TSHR (0.69) | TSHRGPR35TDP1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105392557-A | Adsorbent and analysis system using same | HITACHI HIGH TECH CORP | 2016-03-09 | — | — | CN | disclosed |