Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4519276 | 0.81 | SMN1; SMN2 (0.62) | TDP1L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL5131881 | 0.78 | CYP1A2 (0.56) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11278674 | 0.78 | NPC1 (0.74) | TDP1L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL4514258 | 0.77 | SMN1; SMN2 (0.49) | TDP1L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL28876415 | 0.77 | CYP1A2 (0.55) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16398809 | 0.76 | ALDH1A1 (0.63) | TDP1L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL202432 | 0.76 | TDP1 (1.00) | TDP1L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL28056154 | 0.75 | MAPT (0.58) | TDP1L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL10935498 | 0.74 | NPC1 (0.75) | TDP1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4518562 | 0.74 | ACACB (0.58) | NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-A | Cyanotriazole compounds | OTSUKA PHARMA CO LTD | 2016-03-16 | — | — | CN | disclosed |