SCHEMBL28056171

SCHEMBL28056171

O=C(O)c1ccc(C(=O)O)o1.c1ccc2c(c1)ccc1c3c(ccc12)CCCC3

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.47
KDM4E B2RXH2 3/20 0.47
GLA P06280 2/20 0.47
MAPT P10636 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
TSHR P16473 1/20 0.47
HTT P42858 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
NQO1 P15559 6/20 0.43
ALDH1A1 P00352 3/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.41
WDR5 P61964 1/20 0.40
CYP1A2 P05177 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
ACHE P22303 1/20 0.39
SLC6A2 P23975 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL27702695 0.89 HPRT1 (0.45) HPGDMAPTNQO1ALDH1A1WDR5
Phthalic Acid SCHEMBL27274659 0.87 NR4A1 (0.49) HPGDKDM4EGLAMAPTNQO1
SCHEMBL27403294 0.87 ALDH1A1 (0.45) HPGDKDM4EGLAMAPTL3MBTL1
Benzoic Acid SCHEMBL27487417 0.86 WDR5 (0.41) HPGDMAPTTSHRNQO1ALDH1A1
Phthalic Acid SCHEMBL28754093 0.86 NR4A1 (0.47) HPGDKDM4EGLAMAPTNQO1
Terephthalic Acid SCHEMBL27482447 0.86 RXRA (0.44) HPGDMAPTNQO1ALDH1A1WDR5
Acetic Acid SCHEMBL27295805 0.86 ALDH1A1 (0.46) HPGDKDM4EMAPTNQO1ALDH1A1
SCHEMBL27508487 0.86 HPRT1 (0.45) HPGDMAPTTSHRHSD17B10TDP1
Benzene SCHEMBL27260397 0.85 HPRT1 (0.52) MAPTTSHRHSD17B10TDP1NQO1
SCHEMBL2089665 0.84 HPRT1 (0.54) MAPTTSHRHSD17B10TDP1NQO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105392818-B High-fire resistance high grade of transparency makrolon and preparation method thereof SK化学公司 2017-11-28 CN claimed
CN-107108870-A Prepare the new method of the makrolon with the high grade of transparency and high-fire resistance SK化学公司 2017-08-29 CN claimed
CN-105392818-A Highly heat-resistant and highly transparent polycarbonate ester, and preparation method therefor SK CHEMICALS CO LTD 2016-03-09 CN claimed
CN-107108870-A Prepare the new method of the makrolon with the high grade of transparency and high-fire resistance SK化学公司 2017-08-29 CN disclosed