Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SCN4A | P35499 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15750040 | 0.86 | DYRK1A (0.41) | NPC1RAB9ASMN1; SMN2LMNASCN4A | |
| SCHEMBL29802364 | 0.78 | RAB9A (0.67) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL26932325 | 0.78 | RAB9A (0.67) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL926856 | 0.77 | KDM4E (0.48) | NPC1RAB9ASMN1; SMN2LMNACYP1A2 | |
| SCHEMBL8975216 | 0.74 | KMT2A (0.47) | NPC1RAB9ASMN1; SMN2LMNAUSP2 | |
| SCHEMBL28056267 | 0.73 | KDM4E (0.49) | NPC1RAB9ASMN1; SMN2LMNASCN4A | |
| SCHEMBL17848625 | 0.71 | APP (0.49) | NPC1RAB9ASMN1; SMN2LMNADYRK1A | |
| SCHEMBL19914297 | 0.70 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2LMNASCN4A | |
| SCHEMBL21066386 | 0.70 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2LMNASCN4A | |
| SCHEMBL12357591 | 0.70 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2LMNASCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166156-B | Tyrosine kinase inhibitors, compositions and methods | 贝达药业股份有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-113166156-B | Tyrosine kinase inhibitors, compositions and methods | 贝达药业股份有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-105431427-A | Novel PDE4 inhibitor | MEIJI SEIKA PHARMA CO LTD | 2016-03-23 | — | — | CN | disclosed |