Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | ULK1 | O75385 | 1/20 | 0.40 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31391349 | 0.85 | DYRK1A (0.45) | KDM4EDYRK1ABACE1NPC1RAB9A | |
| SCHEMBL4640466 | 0.85 | DYRK1A (0.45) | KDM4EDYRK1ABACE1NPC1RAB9A | |
| SCHEMBL2614339 | 0.81 | DYRK1A (0.45) | DYRK1ANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL23478832 | 0.78 | DYRK1A (0.42) | DYRK1AULK1ULK2NPC1RAB9A | |
| SCHEMBL29802284 | 0.76 | RAB9A (0.71) | NPC1RAB9ASMN1; SMN2EPHX2LMNA | |
| SCHEMBL26932194 | 0.76 | RAB9A (0.71) | NPC1RAB9ASMN1; SMN2EPHX2LMNA | |
| SCHEMBL29118422 | 0.75 | ULK1 (0.45) | ULK1ULK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20066542 | 0.75 | LMNA (0.43) | DYRK1ANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL1798498 | 0.74 | DYRK1A (0.49) | KDM4EDYRK1ABACE1ULK1ULK2 | |
| SCHEMBL28056200 | 0.73 | NPC1 (0.43) | DYRK1ANPC1RAB9ASMN1; SMN2SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365995-B | Immunomodulators, compositions and methods thereof | 贝达药业股份有限公司 | 2025-03-04 | — | — | CN | disclosed |
| US-11655225-B2 | Antimycobacterial heterocyclic amides | CRESTONE, INC. (US) | 2023-05-23 | — | — | US | disclosed |
| CN-105431427-A | Novel PDE4 inhibitor | MEIJI SEIKA PHARMA CO LTD | 2016-03-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655225-B2 | Antimycobacterial heterocyclic amides | AADAC, CPS1, NAT1 | KDM4E 2100/4885DYRK1A 3890/4885BACE1 4551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.