SCHEMBL926856

SCHEMBL926856

COc1ccc2ncoc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.48
ALDH1A1 P00352 4/20 0.48
RAB9A P51151 4/20 0.48
MEN1 O00255 3/20 0.48
POLB P06746 3/20 0.48
KMT2A Q03164 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
LMNA P02545 2/20 0.48
NPC1 O15118 2/20 0.48
NQO2 P16083 1/20 0.48
HPGD P15428 2/20 0.45
MAPT P10636 2/20 0.45
THRB P10828 2/20 0.45
BLM P54132 2/20 0.45
ALOX12 P18054 1/20 0.45
PTPN7 P35236 1/20 0.45
HTT P42858 1/20 0.45
RECQL P46063 1/20 0.45
MCL1 Q07820 1/20 0.45
TDP1 Q9NUW8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9297195 0.86 TYR (0.43) KDM4EALDH1A1RAB9AMEN1POLB
SCHEMBL926786 0.85 ALDH1A1 (0.48) KDM4EALDH1A1RAB9AMEN1POLB
SCHEMBL29475990 0.85 ALDH1A1 (0.48) KDM4EALDH1A1RAB9AMEN1POLB
SCHEMBL31637723 0.83 RAB9A (0.39) KDM4EALDH1A1RAB9AMEN1POLB
SCHEMBL8975216 0.81 KMT2A (0.47) KDM4EALDH1A1RAB9AMEN1KMT2A
SCHEMBL27394057 0.78 HPGD (0.47) KDM4EALDH1A1RAB9AMEN1POLB
SCHEMBL27563412 0.78 KDM4E (0.49) KDM4EALDH1A1RAB9APOLBSMN1; SMN2
SCHEMBL28056200 0.77 NPC1 (0.43) RAB9AMEN1KMT2ASMN1; SMN2LMNA
SCHEMBL29802293 0.76 RAB9A (0.71) KDM4ERAB9AMEN1POLBKMT2A
SCHEMBL26932219 0.76 RAB9A (0.71) KDM4ERAB9AMEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 808 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117562064-A Application of 6-methoxybenzoxazolin-2-one in inhibiting soil-borne pathogenic bacteria of broad beans 云南农业大学 2024-02-20 CN claimed
CN-115644186-A Application of 6-methoxy-benzoxazoline-2-ketone in trapping meloidogyne incognita 浙江大学 2023-01-31 CN claimed
US-7091360-B2 Process for preparing heteroaryl and unsaturated heterocycloalkylmagnesium reagents and uses thereof AVENTIS PHARMA S.A. (US) 2006-08-15 US claimed
EP-1495007-A4 PROCESS FOR PREPARING HETEROARYL AND UNSATURATED HETEROCYCLOALKYLMAGNESIUM REAGENTS AND USES AXYS PHARM INC (US) 2006-05-03 EP claimed
EP-1495007-A1 PROCESS FOR PREPARING HETEROARYL AND UNSATURATED HETEROCYCLOALKYLMAGNESIUM REAGENTS AND USES AXYS PHARMACEUTICALS, INC. (US) 2005-01-12 EP claimed
US-20040019218-A1 Process for preparing heteroaryl and unsaturated heterocycloalkylmagnesium reagents and uses thereof AXYS PHARMACEUTICALS, INC. 2004-01-29 US claimed
WO-2003087068-A1 PROCESS FOR PREPARING HETEROARYL AND UNSATURATED HETEROCYCLOALKYLMAGNESIUM REAGENTS AND USES AXYS PHARMACEUTICALS, INC. (US) 2003-10-23 WO claimed
EP-0278509-B1 Silver halide photographic emulsion FUJI PHOTO FILM CO LTD (JP) 1996-01-24 EP claimed
EP-0368327-B1 Light-sensitive composition FUJI PHOTO FILM CO LTD (JP) 1995-02-15 EP claimed
EP-0271260-B1 Supersensitization of silver halide emulsions MINNESOTA MINING & MFG (US) 1995-01-04 EP claimed
US-4970141-A ELEVATED SPECTRAL SENSITIVITY IN GREEN WAVELENGTH REGION FUJI PHOTO FILM CO., LTD. (JP) 1990-11-13 US claimed
EP-0368327-A2 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1990-05-16 EP claimed
US-4891305-A LASERS RICOH CO., LTD. (JP) 1990-01-02 US claimed
US-4889796-A CONTAINING BENZOXAZOLE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1989-12-26 US claimed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 US claimed
EP-0278509-A2 Silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 1988-08-17 EP claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP claimed
US-4154616-A BENZOXAZOLE OR NAPHTHOXAZOLE MEROCYANINE DYE FUJI PHOTO FILM CO., LTD. (JP) 1979-05-15 US claimed
US-4057430-A MEROCYANINE THIOHYDANTOIN SENSITIZERS FUJI PHOTO FILM CO., LTD. (JA) 1977-11-08 US claimed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040019218-A1 Process for preparing heteroaryl and unsaturated heterocycloalkylmagnesium reagents and uses thereof SPINT2, CTSV, CTSZ KDM4E 4252/4885ALDH1A1 2466/4885RAB9A 3107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.