Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1815665 | 0.81 | LMNA (0.64) | LMNAAKR1C3AKR1C2ALDH1A1HSD17B10 | |
| SCHEMBL1809801 | 0.80 | LMNA (0.46) | SMN1; SMN2LMNACA2MEN1KMT2A | |
| SCHEMBL1558072 | 0.77 | IKBKB (0.50) | SMN1; SMN2LMNAIKBKBCA2MEN1 | |
| SCHEMBL26412112 | 0.77 | AVPR2 (0.58) | SMN1; SMN2LMNAMEN1KMT2ADRD3 | |
| SCHEMBL15573709 | 0.73 | ALDH1A1 (0.52) | LMNAALDH1A1GAA | |
| SCHEMBL27349927 | 0.71 | LMNA (0.46) | SMN1; SMN2LMNAIKBKBCA2KCNH2 | |
| SCHEMBL12049688 | 0.71 | CA2 (0.69) | SMN1; SMN2CA2MEN1KMT2ATSHR | |
| SCHEMBL1018520 | 0.70 | LMNA (0.59) | LMNACA2AKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL30602792 | 0.70 | LMNA (0.45) | SMN1; SMN2LMNAIKBKBCA2MEN1 | |
| SCHEMBL1017860 | 0.70 | KDM4E (0.45) | SMN1; SMN2LMNACA2KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103415507-B | As the 3-amino-pyridine class of GPBAR1 agonist | HOFFMAN-LA ROCHE LTD. (CH) | 2016-03-02 | — | — | CN | disclosed |