Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26687025 | 0.84 | LMNA (0.49) | LMNAPOLBALDH1A1SMN1; SMN2USP2 | |
| SCHEMBL709637 | 0.81 | LMNA (0.46) | LMNAPOLBALDH1A1SMN1; SMN2SCN9A | |
| SCHEMBL5272865 | 0.81 | LMNA (0.46) | LMNAPOLBALDH1A1SMN1; SMN2SCN9A | |
| SCHEMBL419701 | 0.81 | LMNA (0.46) | LMNAPOLBALDH1A1SMN1; SMN2SCN9A | |
| SCHEMBL16640 | 0.81 | LMNA (0.46) | LMNAPOLBALDH1A1SMN1; SMN2SCN9A | |
| SCHEMBL29195369 | 0.81 | LMNA (0.46) | LMNAPOLBALDH1A1SMN1; SMN2SCN9A | |
| SCHEMBL9579074 | 0.79 | LMNA (0.45) | LMNAPOLBALDH1A1SMN1; SMN2USP2 | |
| SCHEMBL4590639 | 0.77 | — | — | |
| SCHEMBL13143765 | 0.77 | — | — | |
| SCHEMBL16114627 | 0.77 | ALDH1A1 (0.48) | LMNAPOLBALDH1A1SMN1; SMN2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105418546-A | Process for producing optically active cyclic ether ester derivative | DAICEL FINECHEM LTD | 2016-03-23 | — | — | CN | disclosed |