Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.54 |
| ▸ | PTPRC | P08575 | 3/20 | 0.51 |
| ▸ | S100A4 | P26447 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MYC | P01106 | 1/20 | 0.48 |
| ▸ | MAX | P61244 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28207049 | 0.85 | PTGS2 (0.73) | PTGS2POLBRAB9APTGDR2PTPRC | |
| SCHEMBL6391559 | 0.85 | PTGS2 (0.69) | PTGS2POLBRAB9APTGDR2PTPRC | |
| SCHEMBL5935200 | 0.81 | PTGS2 (0.56) | PTGS2POLBRAB9APTGDR2PTPRC | |
| SCHEMBL10448853 | 0.81 | PTGS2 (0.74) | PTGS2POLBRAB9APTGDR2PTPRC | |
| SCHEMBL10904251 | 0.81 | ALDH1A1 (0.63) | PTGS2POLBRAB9APTGDR2PTPRC | |
| SCHEMBL536487 | 0.80 | MEN1 (0.59) | PTGS2POLBRAB9APTGDR2ALDH1A1 | |
| SCHEMBL629839 | 0.80 | PTGS2 (0.59) | PTGS2POLBRAB9APTGDR2PTPRC | |
| SCHEMBL5935201 | 0.80 | PTGS2 (0.55) | PTGS2POLBRAB9APTGDR2PTPRC | |
| SCHEMBL10508753 | 0.80 | PTGS2 (0.55) | PTGS2POLBRAB9APTGDR2PTPRC | |
| SCHEMBL6573092 | 0.80 | PTGS2 (0.55) | PTGS2POLBRAB9APTGDR2PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294415-A | Preparation method of 3-halogenated fluorenone compound | YANTAI GEM CHEMICALS CO LTD | 2016-02-03 | — | — | CN | disclosed |