SCHEMBL28056754

SCHEMBL28056754

Nc1c(F)cc(S(=O)(=O)O)cc1F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.50
CA2 P00918 6/20 0.50
CA9 Q16790 6/20 0.50
CA3 P07451 1/20 0.48
ALDH1A1 P00352 4/20 0.44
NT5E P21589 3/20 0.44
TSHR P16473 3/20 0.44
HSD17B10 Q99714 3/20 0.43
TDP1 Q9NUW8 1/20 0.43
HDAC1 Q13547 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
CA12 O43570 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
LCK P06239 1/20 0.41
FYN P06241 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14743678 0.89 NT5E (0.47) CA1CA2CA9CA3ALDH1A1
Bromide SCHEMBL31457083 0.84 CA1 (0.70) CA1CA2CA9CA3ALDH1A1
SCHEMBL3129078 0.80 LCK (0.44) CA1CA2CA9ALDH1A1NT5E
SCHEMBL5981674 0.80 CA1 (0.54) CA1CA2CA9CA3ALDH1A1
Hydrochloric Acid SCHEMBL27862607 0.78 LCK (0.43) CA1CA2CA9ALDH1A1NT5E
SCHEMBL22396634 0.76 HDAC1 (0.42) CA1CA2CA9ALDH1A1NT5E
SCHEMBL10152040 0.76 CA1 (0.50) CA1CA2CA9CA3HDAC1
SCHEMBL5734698 0.76 CA1 (0.68) CA1CA2CA9ALDH1A1NT5E
SCHEMBL22931126 0.76 ALDH1A1 (0.41) CA1CA2CA9CA3ALDH1A1
SCHEMBL21589346 0.75 ALDH1A1 (0.56) CA1CA2CA9CA3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105542584-B A kind of thermal sensation fluorine carbon functional paint and preparation method containing azobenzene/carbon hybrid material 天津大学 2018-04-03 CN claimed
CN-105542584-A Thermal-inductive fluorocarbon function coating containing azobenzene/carbon-hybrid material and preparation method of thermal-inductive fluorocarbon function coating UNIV TIANJIN 2016-05-04 CN claimed
CN-105542584-B A kind of thermal sensation fluorine carbon functional paint and preparation method containing azobenzene/carbon hybrid material 天津大学 2018-04-03 CN disclosed
CN-105542584-A Thermal-inductive fluorocarbon function coating containing azobenzene/carbon-hybrid material and preparation method of thermal-inductive fluorocarbon function coating UNIV TIANJIN 2016-05-04 CN disclosed