Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 11/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28056842 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPK1SMN1; SMN2FAAHKDM4E | |
| SCHEMBL5448837 | 0.86 | KYAT1 (0.50) | ALDH1A1MAPK1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL27977460 | 0.86 | KYAT1 (0.50) | ALDH1A1MAPK1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL5448834 | 0.86 | KYAT1 (0.50) | ALDH1A1MAPK1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL14059461 | 0.84 | FAAH (0.51) | FAAH | |
| SCHEMBL14059462 | 0.84 | FAAH (0.51) | FAAH | |
| SCHEMBL30720836 | 0.84 | MAPT (0.52) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL28056796 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL28056798 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL30720833 | 0.81 | MAPT (0.51) | ALDH1A1MAPK1SMN1; SMN2KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103732589-B | Can be used as the sulphonamide of the replacement of anti-apoptotic BCL inhibitor | BRISTOL-MYERS SQUIBB CO. (US) | 2016-03-30 | — | — | CN | disclosed |