Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL554720 | 0.81 | CYP1A2 (0.50) | ACACBNAMPTCYP1A2 | |
| SCHEMBL22265089 | 0.79 | ACACB (0.34) | ACACBNAMPTPIK3CDF2RCYP1A2 | |
| SCHEMBL354704 | 0.78 | — | — | |
| SCHEMBL22265097 | 0.77 | F2R (0.34) | ACACBNAMPTPIK3CDF2RCYP1A2 | |
| SCHEMBL27965018 | 0.75 | FBP1 (0.33) | ACACBNAMPTPIK3CDF2R | |
| SCHEMBL29551483 | 0.75 | F2R (0.33) | ACACBNAMPTPIK3CDF2R | |
| SCHEMBL28204819 | 0.73 | GABRA1 (0.42) | — | |
| SCHEMBL4282448 | 0.73 | FBP1 (0.55) | ACACBNAMPTPIK3CDF2R | |
| SCHEMBL6970853 | 0.71 | — | — | |
| SCHEMBL5160047 | 0.69 | PIK3CD (0.35) | ACACBPIK3CDF2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408328-A | sGC stimulators | IRONWOOD PHARMACEUTICALS INC | 2016-03-16 | — | — | CN | disclosed |