Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | TMPRSS6 | Q8IU80 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29880445 | 1.00 | NOS1 (0.35) | NOS1NOS2DGAT1ALDH1A1TSHR | |
| Carbamic Acid SCHEMBL27890450 | 0.85 | ACHE (0.41) | DGAT1ALDH1A1TSHRCA14MAOA | |
| SCHEMBL30234788 | 0.84 | DGAT1 (0.42) | NOS1NOS2DGAT1ALDH1A1CA14 | |
| SCHEMBL28325001 | 0.84 | DGAT1 (0.42) | NOS1NOS2DGAT1ALDH1A1CA14 | |
| SCHEMBL3094 | 0.84 | — | — | |
| SCHEMBL28902273 | 0.84 | DGAT1 (0.42) | NOS1NOS2DGAT1ALDH1A1CA14 | |
| Acetic Acid SCHEMBL1835057 | 0.82 | FFAR3 (0.39) | DGAT1ALDH1A1TSHRMAOAMAOB | |
| Methylamine SCHEMBL25305181 | 0.82 | DGAT1 (0.40) | NOS1NOS2DGAT1ALDH1A1CA14 | |
| Hydrochloric Acid SCHEMBL8549932 | 0.82 | DGAT1 (0.40) | NOS1NOS2DGAT1ALDH1A1CA14 | |
| SCHEMBL30702219 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768792-B | Cinnamamide-hydroxypyridone derivative, and preparation method and application thereof | 浙江工业大学 | 2024-10-18 | — | — | CN | disclosed |
| CN-116987080-A | Macrocyclic compounds with heterocyclic P2' groups as factor XIA inhibitors | 百时美施贵宝公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-116768792-A | Cinnamamide-hydroxypyridone derivative, and preparation method and application thereof | 浙江工业大学 | 2023-09-19 | — | — | CN | disclosed |
| CN-116323566-A | Sulfanone compound and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-110845498-B | Macrocyclic compounds having heterocyclic P2' groups as factor XIA inhibitors | 百时美施贵宝公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-115335373-A | Compound and use thereof | 福宏治疗公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-109563103-B | Modulators of beta-3 adrenergic receptors for the treatment or prevention of disorders related thereto | 艾尼纳制药公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-111954670-A | Sulfonylurea derivatives as NLRP3 inflammasome modulators | 诺瑟拉有限公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-105980384-B | Macrocyclic compounds having a heterocyclic P2' group as factor XIA inhibitors | 百时美施贵宝公司 | 2019-11-15 | — | — | CN | disclosed |
| CN-106459051-B | Macrocyclic FXIA Inhibitors Containing Heterocyclic Groups | 百时美施贵宝公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-106470708-A | Antibody-drug-conjugates and their use for the treatment of cancer | 皮埃尔法布雷医药公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-106459051-A | Macrocyclic FXIA Inhibitors Containing Heterocyclic Groups | 百时美施贵宝公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106456800-A | IGF-1R antibody-drug-conjugates and uses thereof for the treatment of cancer | 皮埃尔法布雷医药公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106132962-A | Macrocyclic compounds having an aromatic P2' group as factor XIA inhibitors | 百时美施贵宝公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-105980384-A | Macrocyclic compounds having a heterocyclic P2' group as factor XIA inhibitors | 百时美施贵宝公司 | 2016-09-28 | — | — | CN | disclosed |
| CN-105745192-A | Substituted phenylalanine derivatives | 拜耳制药股份公司 | 2016-07-06 | — | — | CN | disclosed |
| CN-104981470-A | Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use | Bayer Pharma AG | 2015-10-14 | — | — | CN | disclosed |
| CN-101827596-A | Combinations comprising purine derivatives and other compounds and their use for the treatment of inflammatory and obstructive airways diseases | NOVARTIS AG | 2010-09-08 | — | — | CN | disclosed |
| CN-101426483-A | Purine derivatives as A2A receptor agonists | NOVARTIS AG (CH) | 2009-05-06 | — | — | CN | disclosed |
| CN-101420959-A | Use of 2- (purin-9-yl) -tetrahydrofuran-3, 4-diol derivatives as adenosine A2A receptor agonists | NOVARTIS AG (CH) | 2009-04-29 | — | — | CN | disclosed |