Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5600586 | 0.66 | MAOA (0.30) | — | |
| SCHEMBL5601989 | 0.64 | CYP11B2 (0.31) | — | |
| SCHEMBL5603253 | 0.64 | CYP11B2 (0.31) | — | |
| SCHEMBL5601065 | 0.64 | CYP11B2 (0.31) | — | |
| SCHEMBL2766035 | 0.64 | CYP11B2 (0.31) | — | |
| SCHEMBL5601700 | 0.64 | CYP11B2 (0.31) | — | |
| SCHEMBL5601697 | 0.61 | — | — | |
| SCHEMBL6379009 | 0.54 | NISCH (0.32) | — | |
| SCHEMBL7853833 | 0.53 | TDO2 (0.32) | — | |
| SCHEMBL7845159 | 0.52 | CYP11B2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791715-B | As the tricyclic compound of kinase inhibitor | FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III (ES) | 2016-04-27 | — | — | CN | claimed |
| CN-104684912-A | Inhibitor compounds of phosphodiesterase type 10A | ABBVIE DEUTSCHLAND | 2015-06-03 | — | — | CN | claimed |
| CN-103547580-A | Substituted fused tricyclic compounds, compositions and medical uses thereof | ADVINUS THERAPEUTICS LTD | 2014-01-29 | — | — | CN | claimed |
| CN-102791715-B | As the tricyclic compound of kinase inhibitor | FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III (ES) | 2016-04-27 | — | — | CN | disclosed |
| CN-102574845-B | 1H-imidazo [4,5-c] qualone derivative | NOVARTIS AG (CH) | 2015-09-02 | — | — | CN | disclosed |
| CN-104684912-A | Inhibitor compounds of phosphodiesterase type 10A | ABBVIE DEUTSCHLAND | 2015-06-03 | — | — | CN | disclosed |
| CN-103547580-A | Substituted fused tricyclic compounds, compositions and medical uses thereof | ADVINUS THERAPEUTICS LTD | 2014-01-29 | — | — | CN | disclosed |