Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CETP | P11597 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | UBE2N | P61088 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | LAP3 | P28838 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7156689 | 0.98 | LMNA (0.53) | LMNACYP2D6SPHK1TP53GMNN | |
| Hydrochloric Acid SCHEMBL5353819 | 0.96 | LMNA (0.52) | LMNACYP2D6SPHK1TP53GMNN | |
| Hydrochloric Acid SCHEMBL5350915 | 0.96 | LMNA (0.52) | LMNACYP2D6SPHK1TP53GMNN | |
| SCHEMBL27421723 | 0.89 | LMNA (0.53) | LMNACYP2D6SPHK1TP53GMNN | |
| Fluoride SCHEMBL9761042 | 0.85 | LMNA (0.46) | LMNACYP2D6SPHK1TP53GMNN | |
| SCHEMBL11832847 | 0.84 | OPRM1 (0.52) | LMNACYP2D6SPHK1TP53GMNN | |
| SCHEMBL14900909 | 0.84 | OPRM1 (0.52) | LMNACYP2D6SPHK1TP53GMNN | |
| SCHEMBL15580908 | 0.84 | OPRM1 (0.52) | LMNACYP2D6SPHK1TP53GMNN | |
| SCHEMBL11292697 | 0.83 | TP53 (0.50) | LMNACYP2D6SPHK1TP53GMNN | |
| Hydrochloric Acid SCHEMBL11832535 | 0.82 | OPRM1 (0.50) | LMNACYP2D6SPHK1TP53GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105350316-A | Preparation method of pure cotton fabric finishing liquid | CHENGLU KAIER CLOTHING SUZHOU CO LTD | 2016-02-24 | — | — | CN | disclosed |